Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"compound 48/80"”.
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The Intradermal Skin Test in the Horse: Value as a Diagnostic Modality in Equine Allergies
… wheals created by 5 concentrations of histamine, compound 48/80, and phaseolus vulgaris (PHA) within a normal horse and between 12 normal horses at 0.5 hours, 4 hours, and 24 hours post injection. Minimal variability was detected within individual horses and between 12 horses for histamine and …
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Chemokines as therapeutic targets in systematic inflammatory response syndrome
… and sepsis. Depletion of mast cells by compound 48/80 has also attenuated acute pancreatitis-associated lung injury and sepsis-associated lung injury by attenuating the levels of chemokines. Treatment with an exogenous CX3C chemokine FTK has shown pro-inflammatory effect in acute …
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Sphingosine-1-phosphate in mast cell-mediated allergic responses
… by anaphylatoxin C5a and the secretagogue compound 48/80. S1P induced release of IL-6, a cytokine known to promote development of functionally mature MCTC, from cord blood cultures containing adherent macrophages, and from highly purified macrophages, but not from macrophage-depleted …
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ROLES OF MAST CELL G PROTEIN-COUPLED RECEPTOR KINASE 2 (GRK2) IN ALLERGY AND INFLAMMATION
… enhanced β-hexosaminidase release in response to compound 48/80 (C48/80) but significantly reduced tryptase release in response to the Cathelicidin LL37. Furthermore, absence of GRK2 resulted in increased cutaneous vascular permeability in response to C48/80 in vivo. By contrast, LL37-injection …
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Protein degradation in rat skeletal muscle : intracellular, non-lysosomal enzyme systems and their endocrine control
… treatment of the animals with the degranulator, compound 48/80. Peptides of varying size were generated from radio-actively labelled globin, but no free amino acids were formed; free tyrosine was also not released from azocasein. The pH optimum was 7.5 and the presence of an essential cysteine …