Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 16 of 16 for “"composite scaffold"”.
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Electromagnetic stimulation of a composite scaffold for wound healing
… been investigated as natural sources for tissue scaffolds as synthetic mimicry of the natural extracellular matrix is quite difficult. In addition, gold nanomaterials have been studied for their ability to provide nanostructural cues for cell growth as well as their ability to interact with free …
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Development of a nanoHydroxyapatite-collagen composite scaffold for bone tissue engineering
Scaffolds for tissue engineering must meet certain requirements to make it suitable for use as a bone graft substitute, including a three-dimensional and highly porous structure, with an interconnected pore network to facilitate cell growth and transport of nutrients and metabolic waste products. …
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Design of advanced biobased photocurable formulations: from dynamic covalent network to composite scaffold for tissue engineering
L'abstract è presente nell'allegato / the abstract is in the attachment
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Delivery of hiPSC Derived Cardiomyocytes via an Injectable Nanofibrous Gelatin Polyurethane Composite Scaffold for Heart Tissue Repair
… that hiPSC-CMs cultures on a nanofibrous scaffold, made from an in-house elastomeric polyurethane composite exhibited high viability and retained basic CM functionality after 7 days of culture. To enhance the mechanical compliance with cardiac tissue and accelerate degradation of the …
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The influence of microporosity on the mechanical properties of bulk, scaffold, and composite scaffold biphasic calcium phosphate
… biphasic calcium phosphate (BCP), monolithic BCP scaffolds with multi-scale porosity (macro- and microporosity), and BCP/polymethylmethacrylate (PMMA) composite scaffolds with multi-scale porosity were investigated in this work. The elastic properties of bulk BCP with varying micropore size and …
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A Novel Drug Delivery System Incorporates a Functional Composite Scaffold Derived from Taxifolin with Potential Cytotoxic and Anticancer Effects on Triple Negative Breast Cancer
… taxifolin delivery system via electrospun PCL scaffolds to enhance anticancer and therapeutic efficacy of the drug post-operatively. The Comet assay was utilised to analyse DNA damage and repair in lymphocytes from breast cancer patients versus healthy controls. CCK-8, qPCR and Western Blot …
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A Novel Drug Delivery System Incorporates a Functional Composite Scaffold Derived from Taxifolin with Potential Cytotoxic and Anticancer Effects on Triple Negative Breast Cancer
… taxifolin delivery system via electrospun PCL scaffolds to enhance anticancer and therapeutic efficacy of the drug post-operatively. The Comet assay was utilised to analyse DNA damage and repair in lymphocytes from breast cancer patients versus healthy controls. CCK-8, qPCR and Western Blot …
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Production of temporary bone scaffold reinforced with OPEFB-CMC from oil palm empty fruit bunch
… Current treatment for bone fracture employs the scaffolding approaches which are specifically positioned for a certain period of time. These allow the defective bones to undergo proper healing processes. However, these scaffolds have two issues that need to be addressed; the material’s …
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Enhancing the mechanical properties of a hydroxyapatite-collagen bone surrogate
… synthesis of biomimetic hydroxyapatite-collagen composites is desirable from the perspective of graft elimination and load-bearing support when treating damaged or diseased bone. Bone is an organized network of carbonated hydroxyapatite mineralized collagen, whose strength and toughness is …
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Use Of synthetic solid scaffolds to mechanically support a chondrocyte-seeded peptide hydrogel for articular cartilage repair
… at risk of damage from joint articulation. Solid scaffolds solve this mechanical problem, but often sacrifice bioactivity and integration with native tissue. In order to avoid the drawbacks of each of these approaches, we proposed a composite scaffold approach using a synthetic solid scaffold, …
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Tissue Engineering Cartilage with a Composite Electrospun and Hydrogel Scaffold
… and/or molecular signals. Biodegradable scaffolds serve as a temporary replacement for the tissue until it has regenerated. Two types of scaffolds that have been used in tissue engineering are electrospun scaffolds and hydrogels. We have proposed and fabricated a scaffold for cartilage …
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Functionalised self-assembled peptide hydrogel for cell transplantation
… ability to form a shear-thinning and protective scaffold during administration. Post-injection, our biomaterials have been functionalised to provide relevant biologically active motifs. These motifs can replicate features of the native cellular microenvironment of the brain and present a …
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Functionalised self-assembled peptide hydrogel for cell transplantation
… ability to form a shear-thinning and protective scaffold during administration. Post-injection, our biomaterials have been functionalised to provide relevant biologically active motifs. These motifs can replicate features of the native cellular microenvironment of the brain and present a …
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Biosynthesis of polyhydroxyalkanoates and their medical applications
… materials for use in TE, however, when used as scaffolds in bone TE, PHAs fail to actively bind to the living tissue by means of a biologically active apatite layer or meet the mechanical demands in load-bearing applications. Therefore, these polymers are combined with inorganic bioactive …
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Strategies for the Fabrication of Cellularized Micro-Fiber/Hydrogel Composites for Ligament Tissue Engineering
… have been widely utilized as biomaterial scaffolds to support the growth and differentiation of mesenchymal stem cells toward many tissue lineages including ligament. However, these micro-fiber networks do not possess suitable sizes and shapes for a ligament application and cannot support …
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Load bearing regenerative repairs for the cartilaginous soft tissue of the intervertebral disc
… maintaining an injectable and in situ formable scaffold. To improve the stiffness and fatigue resistance of the hydrogels, low molecular weight acrylated star-copolymers composed of D,L-lactide or trimethylene carbonate with caprolactone were mixed with an aqueous solution of methacrylated …