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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.

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Showing 1 to 20 of 22 for “"complex stability"”.

  1. QSPR modelling of lanthanide-organic complex stability constants

    Svetlitski, Ruslan2004

    tartu

  2. RNA replication by poliovirus RNA-dependent RNA polymerase: effects of residue 5 on elongation complex stability and processivity

    Hobdey, Sarah Elizabeth, author, Peersen, Olve B., advisor, Stargell, Laurie, committee member, Chen, Chaoping, committee member, Wilusz, Carol, committee memberColorado State University. Libraries2011

    … change to form a stable RNA-polymerase complex. After the stable RNA-polymerase complex is formed the polymerase undergoes a second conformational change associated with the addition of the first nucleotide to the primer. It is only after these few steps of initiation that the polymerase …

    colostate Repository record

  3. Rmi1 Is Essential For Early Embryonic Development and Attenuation of Tumor Development

    Chen, Haoyi2010

    … that hRMI1 is required for BLM/TopoIIIα/RMI1 complex stability and function. However, in vivo functions of RMI1 remain elusive. To address this question, I generated RMI1 knockout mice by homologous replacement targeting. While RMI1+/- mice showed no obvious phenotype, deletion of both RMI1 …

    uthsc Repository record

  4. CHARACTERISING A ROLE FOR ACETYLCOENZYME A SYNTHETASE 2 IN THE REGULATION OF AUTOPHAGY

    Azad, Arsalan AfzalUniversity of Cambridge2018

    … in regulation of enzyme activities, protein complex stability as well as epigenetic status off chromatin, is only recently emerging. Among multiple other pathways, the autophagy pathway has now been shown to be directly regulated by protein acetylation and deacetylation. Therefore, it was …

    cambridge Repository record

  5. Seismic assessment strategies for masonry structures

    DeJong, Matthew J. (Matthew Justin)Massachusetts Institute of Technology2009

    … addressed. New analysis methods which focus on stability or strength are presented, and the merits of these strategies are clarified. First, a new parametric graphical equilibrium method is developed which allows real-time analysis and illuminates the complex stability of vaulted masonry …

    mit Repository record

  6. CHARACTERIZATION OF NON-EQUILIBRIUMFLUCTUATIONS DURING FREE-DIFFUSION INHIGHLY-STRATIFIED SOLUTIONS OF GLYCEROL ANDWATER

    CASTELLINI, STEFANOUniversità degli Studi di Milano2023

    … heated from below. Such a system presents a complex stability diagram, determined by the competition between the stabilizing flow of nanoparticles induced by thermophoresis and the destabilizing flow determined by thermal convection. We analyzed Rayleigh- Bénard convection in a suspension of …

    milano Repository record

  7. Preparação e caracterização de complexos multicomponentes contendo ciclodextrinas e benznidazol

    Melo, Polyanne Nunes deUniversidade Federal do Rio Grande do Norte2013

    … as well as the formation of inclusion complexes was also investigated. The interactions in solution were predicted and investigated using phase solubility diagram methodology, nuclear magnetic resonance of protons (RMN) and molecular modeling. Complexes were obtained in solid phase by …

    brazil-ufrn Repository record

  8. Effects of Secondary Forces on the Primary Interaction and Variable Domain Conformation of Antifluorescein Antibodies

    Mummert, Mark EricUniversity of Illinois at Urbana-Champaign2015

    … antibody variable domains as well as impacting complex stability. Although secondary forces do not dictate antibody specificity (the primary interaction) an understanding of these interactions is critical in evaluating the nuances of antibody/antigen interactions. Described within this thesis is …

    uiuc Repository record

  9. Cyclodextrin complexes of antimicrobial agents

    Chauhan, NaynaAston University1995

    … (CyD) due to the formation of a water-soluble complex between the drug and dissolved CyD. This study investigated the interactions of -Cyd and hydroxypropyl--CyD (HP--CyD, M.S. = 0.6) with antimicrobial agents of limited solubility in an attempt to increase their microbiological efficacy. The …

    aston Repository record

  10. Identifying the requirement and mechanism of the dynamic yet kinetically stable ClpXP interface

    Amor, Alvaro JorgeMassachusetts Institute of Technology2017

    … ATP is required for assembly of active ClpXP complexes. Moreover, the IGF loops of ClpX are known to be important for stabilizing assembly. In Chapter 2, I use bio-layer interferometry (BLI) to determine the rates of ClpXP assembly and disassembly under different nucleotide conditions. ATP or …

    mit Repository record

  11. Laser-assisted single-molecule refolding

    Zhao, Rui2012

    … </p> <p>HIV 1 DIS RNAs form a kissing complex in the loop region and proceed to the extended duplex structure with the help of enzymes or other cofactors in the later stage of viral replication. The kissing complex itself is very stable, which makes it a unique optimal model system to …

    wayne-thes Repository record

  12. Studies on the interaction of a single domain of protein G from streptococcus with human Fc and Fab

    Muir, NicolaUniversity of Southampton2009

    … at understanding the individual contributions to complex stability made by amino acid residues known to make contacts with either the Fab or Fc. Specific amino-acid residues that contribute to these binding interactions via a network of hydrogen bonds have been identified and studied by a …

    soton Repository record

  13. Correlating antisense RNA performance with thermodynamic calculations

    Tanniche, ImenVirginia Tech2013

    … free energy and binding percentage of asRNA-mRNA complex were computed by NUPACK software. The expression level was drawn as a function of the minimum free energy. The results showed a weak correlation, but linear trends were observed for low energy values and low expression levels the CFP gene. …

    vt Repository record

  14. Complex formation equilibria of ligands with metal ions of biomedical interest

    JARAQUEMADA PELAEZ, MARIA DE GUADALUPEUniversità degli Studi di Cagliari2016

    … In these terms, thermodynamics and kinetics of complex formation are very important for a correct understanding of the role of metal ions in human diseases. During my PhD work, some new ligands were synthesized and their complex formation equilibria with toxic, essential and other metal ions of …

    cagliari Repository record

  15. Characterisation of calcium/calmodulin-dependent protein kinase kinase 2 in prostate cancer

    Stewart, LornaQueen's University Belfast2020

    … Gemin4 and ARCN1. Gemin4 is a member of the SMN complex whose function is in miRNA biogenesis and formation of the spliceosome. ARCN1 is the delta subunit of the COPI coatomer complex which traffics proteins from the Golgi to the ER. The Gemin4 interaction is mediated by the Novel CaMKK2 Binding …

    qu-belfast Repository record

  16. Insights into the structure and aggregation of lens crystallins and other aggregation-prone proteins

    Grosas, Aidan2020

    … as a prelude to such studies on the more complex crystallins. Chapter 2 details the structural characterisation of the disulfide-linked gammaS-crystallin dimer, an oxidative product in the aging lens. X-ray crystallography revealed an intermolecular disulfide bond from C24-C24' and two …

    aus-cath Repository record

  17. Insights into the structure and aggregation of lens crystallins and other aggregation-prone proteins

    Grosas, Aidan2020

    … as a prelude to such studies on the more complex crystallins. Chapter 2 details the structural characterisation of the disulfide-linked gammaS-crystallin dimer, an oxidative product in the aging lens. X-ray crystallography revealed an intermolecular disulfide bond from C24-C24' and two …

    anu Repository record

  18. Identification of novel cellular components associated with early HIV-1 nucleoprotein complexes

    Schweitzer, Cameron J.Creighton University2012

    … in HIV-1 replication. The viral nucleoprotein complexes (NPCs) formed during early HIV-1 infection represent potential targets for antiviral therapy. Despite extensive research the structure and composition of these structures remain poorly characterized. To better characterize these …

    creighton Repository record

  19. Redox properties of Bis-Triarylamines and ligand properties of Thianthrenophane

    Amthor, StephanUniversität Würzburg

    … coordination to small ions or molecules. For the complexation of silver(I) perchlorate, the complex stability constants of thianthrenophane logK1=5.45 and of thianthrene logK2=9.16 were determined by UV/Vis titration. Single competition transport experiments with ten metal salts demonstrate a very …

    wurz-thes Repository record

  20. Generation and application of recombinant antibody fragments for prostate cancer detection.

    Hayes, ConorDublin City University2010

    … greatly enhanced soluble protein expression and stability while also facilitating the rapid kinetic analysis of candidate antibodies by Biacore. A differential expression profile of an anti-fPSA scFv and reformatted scAb was performed by ELISA. Individual antibodies isolated from the ‗biopanning‘ …

    dcu Repository record

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