Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"complement C1q"”.
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A Molecular Basis for Macrophage Control of Enteric Nervous System Function
… mediators of this crosstalk. Here we identify complement component 1q (C1q) as a macrophage product that regulates gut motility. Macrophages were the predominant source of C1q in the mouse intestine and most extraintestinal tissues. Although C1q mediates complement-mediated killing of bacteria …
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The role of complement FH and apoE interactions in the regulation of Aβ1-42 and C1q-mediated complement activation
… (Aβ) protein. Aβ activates the classical complement pathway by binding to C1q that may sustain inflammation, hamper Aβ clearance and therefore promote accumulation of Aβ deposits in the brain and affect the integrity of the blood-brain barrier. Depending on context, binding of apoE to C1q …
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Biochemical characterisation of a novel vaccine candidate against Trypanosoma vivax, the cell surface glycoprotein IFX
… of IFX than the protective counterpart. Complement recruitment accounts for a large component of IFX-elicited immunity in mice, but IFX is a bovine vaccine candidate, so an assay was designed to test complement C1q recruitment to specific bovine IgG isotypes to help fine tune a bovinised …