Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"competence genes"”.
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The contribution of competence system to the virulence of Streptococcus pneumoniae
Competence induction in Streptococcus pneumoniae (pneumococcus) is initiated by the binding of the 17-amino acid competence stimulating peptide (CSP) to its membrane-associated histidine sensor kinase ComD. ComD autophosphorylates and subsequently phosphorylates and activates its cognate response …
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Molecular dissection of competence regulated virulence in Streptococcus pneumoniae
… to improving genome plasticity, a natural competence system directly contributes to pneumococcal virulence during pneumonia and bacteremia, independent of DNA uptake. Competence is activated when the competence stimulating peptide (CSP), encoded by the comC gene, is processed and exported …
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Laboratory evolution and natural transformation in Acinetobacter baylyi ADP1
… inhibited by the evolutionary instability of the competence, the large homology requirement for the efficient transformation of DNA into the ADP1 genome, and incomplete knowledge regarding the composition and regulation of the protein complex involved in DNA uptake. Chapters 1 and 2 describe an …
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Towards Novel Methods of Mutagenesis for Histophilus somni
… phagocytic cells, and many others. To identify genes responsible for virulence, an efficient mutagenesis system is needed. Mutagenesis of H. somni using allelic exchange is difficult due to its tight restriction modification system. Mutagenesis by natural transformation in Haemophilus influenzae …