NDLTD logo NDLTD Union Catalog and Global ETD Search

Global ETD Search

Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.

Results

Showing 1 to 20 of 30 for “"colorectal carcinoma"”.

  1. Hereditary non-polyposis colorectal carcinoma (HNPCC) : morphological and immunohistochemical studies

    Holm, HannesDivision of Anatomical Pathology2005

    Families with hereditary non-polyposis colorectal carcinoma (HNPCC) are not uncommon along the West-Coast of South Africa. These patients present with early onset carcinomas mostly colorectal, predominantly in the right colon. They may develop tumours of other organs, including uterus, breast, …

    cape-town Repository record

  2. Assessing the Role of Dietary Polyamines on the Continuum of Colorectal Carcinoma

    Vargas, Ashley JoyThe University of Arizona.2013

    … ~70% efficacy in preventing premalignant colorectal adenomas (CRA) in a clinical trial; however, high polyamine intakes mitigated this preventative action. Further, dietary polyamines increase the dysplasia of CRA in initiated animal models of colorectal cancer (CRC) and are hypothesized …

    arizona-thes Repository record

  3. Detection of colorectal carcinoma-associated antigens using specific antibodies against human milk oligosaccharides

    Law, Kevin L.Virginia Polytechnic Institute and State University1986

    … homologous haptens as gangliosides in the human colorectal carcinoma cell line SW'lll6. Sialyltetrasaccharide b-ceramide was detected in the monosialylganglioside fraction from human meconium and a total ganglioside fraction from SWlll6 cells on thin layer chromatograms by radioimmune staining …

    vt Repository record

  4. Structural analysis of glycolipid-derived oligosaccharides from metabolically radiolabelled colorectal carcinoma SW1116 cells

    Tarrago-Trani, Maria T.Virginia Tech1991

    … carbohydrate portion of glycosphingolipids from colorectal carcinoma cells, SW1116, by metabolically labelling the cells with radioactive monosaccharide precursors. SW1116 cells (1 x 10⁶) metabolically labelled with 222 μCi/ml of either 6-[³H]-D-galactose (25 Ci/mMol) or 6-[³H]-D-glucosamine (38 …

    vt Repository record

  5. Novel Oligomeric Fluoropyrimidines and Their Efficacy for the Treatment of Colorectal Carcinoma Independent of p53 Mutation

    Dominijanni, AnthonyWake Forest University2017

    The treatment of advanced stage colorectal carcinoma (CRC) is rarely achieved with today’s standard of care, including 5-fluorouracil (5-FU). Resistance to 5-FU is unfortunately frequent in CRC partially due to the dependency 5-FU displays towards normal p53 function, a tumor suppressor protein …

    wfu Repository record

  6. Expression of Markers for Autophagy and Necroptosis in Colorectal Carcinoma // Експресия на маркери за автофагия и некроптоза при дебелочревен карцином

    Стефанова, Надежда, Stefanovа, NadezhdaMedical University of Varna2019

    Колоректалният карцином (КРК) е злокачествено заболяване, чиято честота в последните години непрекъснато нараства. През последните години бяха разработени редица обещаващи туморни маркери, допринасящи за ранното диагностициране, прогностична оценка и мониториране на заболяването. При пациенти с КРК …

    varna Repository record

  7. The histopathology and immunohistochemical expression of cell cycle regulators and mismatch repair gene proteins in colorectal carcinoma : a comparative study

    Sookhayi, RaveendraDivision of Anatomical Pathology2015

    Introduction: It has been reported that HNPCC colorectal carcinomas demonstrate a better prognosis compared to sporadic carcinoma, however the exact mechanism for this is still uncertain. It is possible that tumour morphology, location and cell cycle markers may be indicators of the underlying …

    cape-town Repository record

  8. Investigating the clinicopathological spectrum and associated genetics of colorectal carcinoma in young (<60 years of age) patients in the Western Cape Province

    Aldera, AlessandroDepartment of Pathology2025

    The incidence of colorectal carcinoma (CRC) in young patients is rising in sub-Saharan Africa, and is set to become a major public health problem within the next decade. Despite this, there is a paucity of large-scale genomic studies in the subregion. To investigate driver genes, oncogenic …

    cape-town Repository record

  9. Pre-operative determination of Carcinoembryonic Antigen (p-CEA) as an independent prognostic factor of Disease Free Survival (DFS) in patients treated for colorectal carcinoma

    CAVALLARO, MARIO PIERPAOLOUniversità degli studi di Catania2015

    … un gruppo di pazienti trattati radicalmente per carcinoma colorettale, se la determinazione dell’antigene carcinoembrionario (p-CEA) possa avere una valenza prognostica e costituire un fattore di rischio indipendente in relazione al disease free survival. BACKGROUND: Il p-CEA sembra essere …

    catania Repository record

  10. Regulatory Mechanisms of Mitotic Catastrophe Induced by Doxorubicin

    엄, 영우2011

    … mechanisms of mitotic catastrophe in human colorectal carcinoma cells. MATERIALS AND METHODS: We used human hepatoma (Huh-7) and human hepatocellular carcinoma cell lines (SNU-354, -398, -449, and -475) to distinguish the mode of low doses (LD) of doxorubicin-induced cell death from that of …

    ajou Repository record

  11. Decoding Copy Number Substructure and Evolution From Single Cell Genomics

    Conterno Minussi, Darlan, <p>0000-0001-8856-4625</p>2023

    … the liver and pleural effusion and two matched colorectal carcinoma and its matched metastatic tumors.</p>

    uthsc Repository record

  12. Part I: Evaluation Of Russian Synthetic Compounds As A Potential Source Of New Drug Leads Agains Breast And Colon Cancer Part Ii: Isolation Of Beta-amyrin Formate From Eucalyptus Viminalis Labill And Investigation Of Its Colon Cancer Activity

    Cohanoschi, Mihaela

    … two types of cancer: human breast SK-Br-3 and colorectal carcinoma HT-29. The bioassay results show that seven of the new synthetic Russian compounds can be considered new drug leads, based upon their low toxicity and efficacy in slowing the growth of human breast cancer and colon cancer cells. …

    ucf

  13. A novel genomic approach to multiple cancer diagnostics using mutations in blood bound EV RNA: Machine Learning Methods For Biomarker Detection and Protein Mutation Assessment

    Oliver, JamieOxford Brookes University2023

    … of cancers such as pancreatic ductal adenocarcinoma (PDAC), which is often diagnosed in later stages. Extracellular vesicles (EVs) released into the blood from tumour cells make good biomarkers for this purpose by protecting their nucleotide cargo from the harsh environment, reflecting the …

    oxford-brookes Repository record

  14. Investigating the molecular dynamics of gene re-silencing following treatment with epigenetic therapies

    Patil, VibhaUNSW, Sydney2015

    … exposure, a model gene (MLH1) and cell line (the colorectal carcinoma cell line RKO) were identified and validated. Gene reactivation was dependent on DNMT1 depletion and hypomethylation, nucleosome eviction and the acquisition of active histone marks at the MLH1 promoter. However, close …

    unsw Repository record

  15. Metabolic Manipulation of Glutathione as an Anticancer Therapeutic Target

    Turnbull, Patrick Carson2020

    … seemingly dictated cell fate, whereby HT29 colorectal carcinoma cells displayed decreased cell survival, increased H2O2 and decreased glutathione. CCD 841 normal colon cells were insensitive to palmitoylcarnitine despite increased H2O2, yet maintained glutathione. HepG2 hepatocarcinoma …

    york Repository record

  16. The Role Of ROS-mediated ERK and JNK Activation In The Induction Of Autophagy And Apoptosis In Tumour Cells By A Novel Small Molecule Compound

    WONG CHEW HOOI2009

    … autophagy and apoptotic cell death in human colorectal carcinoma cells. It was later discovered that the ability of C1 to induce autophagy is not limited to a single cell line. Of importance, this study supported the existence of non-canonical autophagy induced by C1. Whereas, silencing of …

    nus Repository record

  17. Targeted Drug Delivery with Cyclodextrin-based Nanocarriers and Focused Ultrasound Triggering

    Xu, DoudouUniversity of Dundee2014

    … treatments to 4 live mice bearing tumours (human colorectal carcinoma, up to 1059.71 mm3) under anaesthesia with full recovery.<br/>Conclusions: The study demonstrated the possibility of translation of the constructed ?-CD derivative to potential clinical use as a delivery vehicle for DOX using …

    dundee Repository record

  18. Genomic analysis in human solid tumours:Copper Homeostasis Genes in Colorectal cancer

    SPAMPINATO, GIORGIAUniversità degli studi di Catania2015

    … mutations in copper homeostasis genes (CHGs) in colorectal cancer, and such analysis, performed on 228 colorectal tumor samples, has revealed that inactivating mutations are extremely rare in CHGs. 2. The collection of whole transcriptome profiles by oligonucleotide microarrays represents the …

    catania Repository record

  19. The healthy effects of L. barbarum on in vitro cell models

    RUSSO, ANGELAUniversità degli studi di Catania2015

    … such as malignant melanoma, renal cell carcinoma, colorectal carcinoma, and lung cancer. Besides the great variety of association studies, there is a need of studies to unravel its therapeutic effects at the biochemical level. In our study, we demonstrate that Goji dry extracts do not …

    catania Repository record

  20. The Treatment of Solid Tumours with Complete Freund's Adjuvant

    Carroll, Christina2016

    … not, however, found to be effective in the CT26 colorectal carcinoma and the DEN-induced Hepatocellular carcinoma. Combination therapy with CFA and anti-CTLA-4, which blocks the inhibitory effects of CTLA-4 on T cells, did not improve CFA treatment efficacy in either the P815 or 4T1 models, but …

    aus-cath Repository record

Page 1 of 2