Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 9 of 9 for “"colonization factors"”.
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Mucins regulate virulence and colonization factors in Streptococcus pneumoniae
… Second, I identify that mucins downregulate colonization factors in S. pneumoniae, modulating microbe-microbe interactions between nasopharyngeal bacteria. Together, these results uncover novel mechanisms for how mucin tames opportunistic pathogens and provides insight for the development of …
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The Colonization Strategies of Nontypeable Haemophilus influenzae - Bacterial Colonization Factors and Vaccine Development
… currently known, and identify novel, bacterial factors involved in the key processes of colonization and pathogenesis, namely adherence to host tissue and evasion of the host innate immunity. We have shown that the NTHi virulence factor Protein E mediates innate immune evasion by interacting …
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Studies on the Expression and Regulation of Enterotoxins and Colonization Factors in Enterotoxigenic Escherichia coli (ETEC)
… disease is established in the small intestine. Colonization factors (CFs) on the bacterial surface mediate adhesion to the intestinal epithelium and diarrhoea is manifested by the actions of a heat-stable (ST) and / or a heat-labile (LT) enterotoxin. Two of the most common CFs in strains …
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Analysis of Bacterial-Host Interactions Between Campylobacter jejuni and the Avian Host During Commensalism
… C. jejuni promotes an asymptomatic, intestinal colonization of many animals, especially avian species, to result in commensalism. The primary route of transmission to humans is through the consumption or handling of undercooked poultry meats, making C. jejuni of particular importance to the …
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Butyrate Sensing by Campylobacter jejuni Impacts Bacterial-Host Interactions
… indicated that bumR is important for early colonization. This contrasts with a human volunteer infection study that demonstrated bumR is essential for infection of humans. Mutational analyses of genes within the BumSR regulon in the natural avian host revealed additional colonization factors …
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Whole Genome Sequencing of Enterotoxigenic Escherichia coli
… on a global level and to search for novel colonization factors (CFs) using both classical and cutting-edge genomic techniques. Using whole genome sequencing and epidemiological data of 362 human ETEC isolates collected during three decades from all over the world, we studied the population …
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Studies of Carbohydrate-Binding Proteins from Enterotoxigenic Escherichia coli
… to the small intestinal epithelium, mediated by colonization factors (CFs). Two of the most common CFs are CFA/I and CS6. CFA/I is a fimbriae with a major subunit, CfaB, and a minor subunit, CfaE. CS6 is non-fimbrial and composed of two major subunits, CssA and CssB. The potential carbohydrate …
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Epidemiology, molecular characterisation and toxin regulation of enterotoxigenic Escherichia coli (ETEC) isolated from children with diarrhoea
… as well as the role of host environmental factors in the regulation of the ETEC enterotoxins. We studied the prevalence, seasonality, antibiotic resistance and severity of disease of diarrhoeas caused by DEC in children aged less than five years in two areas in Bolivia over a period of four …
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Bifidobacterial interactions with human milk oligosaccharides and their combined potential for the advancement of infant nutrition
… interact with a wide range of microbial and host factors, and may influence overall host health. Given the increasing reliance on infant formula in populations where breastfeeding is not feasible, understanding the beneficial potential of HMOs to mimic the advantages of breast feeding is crucial. …