Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 811 for “"colon"”.
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Colon Cancer Survivorship Experiences
The purpose of this project is to explore potential social cognitive and psychosocial predictors of lifestyle changes, including diet and physical activity behaviors, in a sample of colorectal cancer survivors who are at high risk of developing a second colorectal cancer. Participants, recruited …
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Colon Cancer Initiation and Progression
… We have developed an isogenic human colonic epithelial cell (HCEC) model to identify suppressors of anchorage-independent growth by conducting a soft agar based shRNA screen within the cohort of CAN-genes. Remarkably, depletion of 65 of the 151 CAN-genes tested collaborated with …
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Neuroepithelial Signalling in the Colon
… revealed a relative paucity of TRPV4 mRNA within colonic sensory neurons in contrast to the expression of other algogenic receptors and the considerable stimulatory effect of TRPV4 on colonic afferent activity, indicating that non-neuronal cells such as those of the gut mucosa may also contribute …
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Somatic evolution in human blood and colon
… of somatic evolution: blood for clonal dynamics; colon for mutational processes. Blood presents an opportunity to study normal human clonal dynamics, as clones mix spatially and longitudinal samples can be taken. We isolated 140 single haematopoietic stem and progenitor cells from a healthy 59 …
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Diffuse reflectance spectroscopy of human colon tissue
… spectra were collected from adenomatous colon polyps (cancer precursors) and normal colonic tissue of patients undergoing colonoscopy. To analyze the data, an analytical model was developed based on the diffusion of light in tissue. The model was formulated in terms of the absorption and …
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The Role of SOX2 in Colon Cancer Progression
… cells in a dormant state. This phenomenon allows colon cancer cells to escape from cytotoxic drug therapy directed at rapidly dividing cells and cause treatment failure and disease relapse.
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Microtubule Organisation in Normal and Colon Cancer Cells
Abstract+ ApicoNbasal" polarisation" of" epithelial" cells" is" essential" for" normal" function," with" the" rearrangement" of" the"microtubule" cytoskeleton" on" differentiation" critical" for" the" establishment" of" polarity." "During" this" process,"microtubules" reorganise" to" …
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Polyunsaturated fatty acid requirements of murine colon adenocarcinomas
… requirements of three transplantable murine colon adenocarcinomas, the MAC13, MAC16 and MAC26, were evaluated in vitro and in vivo. When serum concentrations became growth limiting in vitro, proliferation of the MAC13 and MAC26 cell lines was stimulated by linoleic acid (LA) at 18μM and …
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Genistein suppresses colon cancer metastasis through epigenetic regulations
… in the United States. Approximately 90% of colon cancer deaths arise from cancer metastasis, the process by which primary tumors invade into and start to proliferate in a distant new site. Dietary factors are closely associated with development and progression of colon cancer. Genistein, one …
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Targeting the tight junction : immunotherapy of colon cancer
A33 is a cell surface glycoprotein of colon epithelium with a long clinical history as a target in antibody-based cancer therapy. Despite being present in normal colon, radio-labeled antibodies against A33 are selectively retained by tumors at long time points. Accordingly, we have studied the …
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Construction of a mouse model of colon cancer
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Biology, 1997.
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Stromal Fibroblasts Restrain The Rate of Colon Cancer Progression and Metastasis By Suppressing Regulatory T Cells and Colon Cancer Stem Cells
… anti- tumor immunity and stemness features in colon cancer cells.</p>
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Role of Retinol in Colon Cancer Invasion and Metastasis
No abstract prepared.
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Factores predictivos de fuga anastómica en cáncer de colon
… de fuga anastomótica tras resección de colon por cáncer, así como crear una herramienta útil para predecir el riesgo de fuga anastomótica, basada en los resultados del análisis multivariante. Material y métodos: Estudio prospectivo y multicéntrico que incluye 52 hospitales españoles. Un …
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The microbiota and colon cancer risk: cause or consequence?
… the host and microbiota throughout the course of colon cancer development in mouse models of sporadic and familial CRC to elucidate their contribution to disease. Our aim was to identify changes in each of these criteria and establish their temporal relationships in order to generate a timeline of …
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Effect of Soyasaponin Fractions on Human Colon Cancer Cells
… B, as anticarcinogenic agents on the human colon adenocarcinoma cell line Caco-2. Experiments were conducted to determine the effects of purified soyasaponins on cell proliferation, Protein Kinase C (PKC) activity, and cell morphology in cultures of Caco-2 cells. Treatment of cells with …
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Inflammation enhanced colon cancer & natural anti-cancer plant compounds
… their ability to prevent inflammation-enhanced colon cancer, using the dextran sulfate sodium/ azoxymethane mouse model. GKB (500 µmol/kg diet daily), GE (providing an equal dose of GKB) and broccoli protected against some aspects of inflammation, including cyclooxygenase-2 levels in colonic …
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Polygalacturonate lyase activity in Bacteroides from the human colon
… on degradation of dietary fiber by the human colon bacteria, a number of Bacteroides strains from the human colon have been found to degrade polygalacturonic acid and/or pectin. Four of these strains were examined for presence of polygalacturonate lyase (PGAL). The Bacteroides strains studied …
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