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Showing 1 to 6 of 6 for “"cold-shock domain"”.
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Cold Shock Domain Proteins in Normal and Leukemic Hematopoiesis
<p>Cold shock domain (CSD) proteins are the most evolutionarily conserved family of nucleic-acid binding proteins. There are four functional genes that contain CSDs in humans and mice: YBX1, MSY4, MSY2, and CSDE1. YBX1 is overexpressed in most cancers, and is frequently associated with poor …
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Stress-induzierte posttranslationale Modifikationen des Y-box Proteins-1 (YB-1) beinhalten Acetylierung und Phosphorylierung
YB-1 is a member of the cold-shock domain protein superfamily. It performs a wide variety of cellular functions, including transcriptional and translational regulation, DNA repair, drug resistence and stress responses to extracellular signals. We demonstate increasing levels of acetylated …
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Identifizierung und Kartierung von nukleären Import- und Exportsignalmotiven innerhalb des Y-box-bindenden Proteins-1 (YB-1)
… and transplation. YB-1 consists of three domains: the N-terminal glycine-rich sequence, the cold shock domain (CSD) and the C-terminal domain. The latter contains alternating acidic and basic amino acids and takes part in a number of protein-protein interactions. Shuttel between the cell …
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The N-terminal Domain of the Y-box Binding Protein YB-1 Plays a Major Role in Cell Proliferation and Apoptosis
… binding protein, YB-1, is a member of the cold shock domain superfamily of proteins. It is involved in a plethora of cellular functions, including cell proliferation. The molecular mechanisms governing the involvement of YB-1 in cell proliferation are still unclear. Earlier studies done in …
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Dissecting key biomass and adaptation traits of Miscanthus through genetic mapping, exploring mechanisms of cold tolerance, and flowering time in Miscanthus and Saccharum
… need for developing new cultivars with superior cold tolerance that could be optimized for regions with severe winters. Three complementary studies on the genetics of overwintering ability of Miscanthus were conducted: 1) an interconnected population consisting of three full-sib families each …
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Identifizierung und Charakterisierung von Genen für die Entwicklung des cerebralen Cortex
… besitzt mit der stark konservierten putativen "cold-shock"-Domäne die Fähigkeit, mit DNA und RNA zu interagieren und somit potentielle Transkriptionsfaktor-Aktivität.Zur Funktionsanalyse von Maus-PIPPin in der Corticogenese wurde das Gen kloniert und mittels homologer Rekombination inaktiviert. …