Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"cold denaturation"”.
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Direct visualization of cold denaturation of cytochrome-C Using Small Angle X-Ray Scattering
We present the first comprehensive study of the cold denaturation of proteins using Small Angle X‐Ray Scattering. The radius of gyration of equine Cytochrome‐C is determined for varying salt and denaturant conditions at temperatures ranging from ‐25 to 60 degrees Celsius. Radius of gyration …
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NMR Investigations of Structure in Pressure and Cold Denatured Proteins
… temperatures and pressures used to perform the cold denaturation studies, hydrogen exchange rates in model amides were measured at various temperatures and pressures to determine the effect of the extreme conditions. These reaction rates are compared to those obtained by correcting extant data …
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Structural And Mechanistic Elucidation Of The EF-hand In LETM1 Ca2+/H+ Antiporter Function
… regiospecific unfolding in response to hot and cold denaturation above 0 °C and a pKa in the physiological range of pH fluctuations. Further, this thesis defines an approach that leverages the accuracy of AlphaFold to guide nuclear Overhauser effect (NOE) assignments during NMR-based protein …
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A path to biodiscovery: isolating Antarctic ascidian-associated bacteria and screening genomes for secondary metabolite-encoded biosynthetic gene clusters and signatures of cold adaptation
… exploring the microbiome for additional cold-water biosynthesized natural products is of interest given recent metagenome results that suggest substantial natural product biosynthetic potential. To advance this research requires investigating cultivation strategies for the …