Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 27 for “"cold chain"”.
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E-Commerce cold chain fulfillment
… shipped, they require a low cost, effective cold chain fulfillment method so as to keep integrity, ensure speed at an affordable low cost for the end consumer. Our research, in partnership with one of the big PCPG items, addressed four aspects of the fulfillment process: Shipments routing, …
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Predicting the thermal performance of bio-based cold chain packaging system
Cold chain logistics play a critical role in ensuring the safe transport of temperature-sensitive products such as pharmaceuticals, biologics, and perishable foods. Maintaining stable internal temperatures within insulated shipping containers (ISCs) requires an in-depth understanding of how …
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Analyzing the level of service and cost trade-offs in cold chain transportation
… transportation cost and the level of service in cold chain transportation. Its purpose is to find the relationship between transportation cost and the level of service in cold chain transportation. Regression models are built to quantify the additional cost of superior quality cold chain for both …
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Leveraging digital tools and analytics for temperature management in cold chain systems for gene therapies
… maintaining ultra low temperatures within the cold supply chain from the manufacturing plant and throughout distribution to the customer. In comparison to traditional cold chain medicines such as most vaccines, gene therapies are high-value, low-volume products and assurance of the product …
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Strategic development of a manufacturing execution system (MES) for cold chain management using information product mapping
… The goal of this thesis is to investigate cold chain management as an expanded functionality for an MES. The thesis attempts to identify best practices for the strategic implementation of an MES in the management of cold chain vaccine products. While the concepts presented in this thesis …
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A Dual Resonant Microstrip Antenna for UHF RFID in the Cold Chain Using Corrugated Fiberboard as a Substrate
… die. Tracking goods throughout the food supply chain increases the efficiency of recall of tainted goods and thus will help reducing food borne illness. Passive UHF RFID has been widely accepted to be a technology capable of increasing supply chain efficiency. Passive UHF RFID tags designed for …
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An assessment of the Measles immunisation status and management in Engela district, Ohangwena region
… to assess measles coverage, vaccine and cold chain management. The data was analysed using Epi Info.7 software and setting p-values of 0.05 for statistical significance. A total of 162 parents/caregivers of the children aged between 9-59 months were interviewed and 17 public health …
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Mathematical modelling of applied heat transfer in temperature sensitive packaging systems. Design, development and validation of a heat transfer model using lumped system approach that predicts the performance of cold chain packaging systems under dynamically changing environmental thermal conditions.
Development of temperature controlled packaging (TCP) systems involves a significant lead-time and cost as a result of the large number of tests that are carried out to understand system performance in different internal and external conditions. This MPhil project aims at solving this problem …
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Estudio de prefactibilidad sobre la instalación de una empresa que brinde el servicio de logística integral para empresas agroexportadoras
… fresh agricultural products chosen keeping the cold chain in all the stages that must pass before being exported to compete in the international market.
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Using real-time truck transportation information to predict customer rejections and refrigeration-system fuel efficiency in packaged salad distribution
Companies that operate cold supply chains can greatly benefit from information availability and data generation. The abundance of information now available to cold chain operators and harvested from every echelon of the supply chain, ranging from the procurement process to the sales and customer …
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Eventing architecture : RFID and sensors in supply chain
… provide an implementation of Track and Trace and Cold-Chain model applications to demonstrate our architecture.
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Development of thermostable affinity reagents for low-cost, paper-based medical diagnostics
… denaturation. In contexts where continuous cold chain storage may be infeasible, the resulting loss in binding activity can manifest as diminished assay sensitivity, leading to adverse clinical outcomes and eroding patient trust in the diagnostic format.
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Experimental technique for optimizing aerosolized vaccine efficacy by Erika J. Sandford.
… vaccines for the developing world, where cold chain systems are impractical and the use of hypodermic needles can be unsafe. However, more research is needed to determine optimal parameters for vaccine aerosolization. This thesis presents an experimental setup to test Aerovax, a device …
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Intradermal needle-free powdered drug injection
… formulations of vaccines to address the cold chain problem-the cost and risk of transporting temperature sensitive vaccines to developing countries.
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Versatility of M13 bacteriophage in medicine : vaccine storage and cancer diagnostics
… addresses the problem of vaccine storage and the cold chain (requirement to store vaccines at 2-80C or lower). The need for refrigeration leads to high cost, difficult field delivery, and high potential for vaccine instability. By capitalizing on the liquid crystalline nature and unique …
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Looking at the Map, Together: Modeling Treatment Center Location Selection and its Effects on Access to Gene Therapy in Brazil
… make it difficult to travel. On the other hand, cold chain requirements make shorter transportation preferable for gene therapies, and few centers have prior experience handling them. Using multi-criteria optimization modeling paired with local input, this thesis explores different approaches to …
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High Velocity Supply Chain: Redesigning a Long Lead Time, Short Shelf Life Supply Chain
… such as Bell. Bell must manage an inbound supply chain with worst case parameters: expensive, cold chain material with long lead times and short shelf lives. Historically, Bell has scrapped over $ 1M/year of these products due to expiration, and meanwhile, multiple stockout events every year …
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Application of polyhedrin protein microparticles for in vivo vaccine and biologics delivery: a proof-of-concept study
… inherent vaccine instability results in strict cold-chain maintenance guidelines to preserve vaccine efficacy, which in turn increases costs. Consequently, underserved healthcare systems are often unable to afford vaccination programmes. In the case of biologic based antivirals, chemical …
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Investigation of Novel Prophylactics Against Human Rotavirus Using Gnotobiotic Pig Models
… this, currently used vaccines require constant cold-chain storage to maintain vaccine stability, and those resources can be scarce in LMICs. These areas continue to maintain a high burden of HRV morbidity and mortality, and more efficacious vaccines are needed. The gnotobiotic (Gn) pig model of …
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Protein Thermal Stabilization and Delivery via Adsorption onto Porous Silicas
The cold chain is a problem that affects the whole pharmaceutical industry: in 2019, 45% of new FDA approved drugs required refrigeration or freezing. It is estimated that biopharma loses around 35 billion dollars every year due to failures in temperature control logistics. Proteins, the main …
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