Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 233 for “"cognitive deficits"”.
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Cognitive deficits in chronic fatigue syndrome
This thesis focuses on cognition in Chronic Fatigue Syndrome (CFS). Many patients report difficulties such as `fuzzy' thinking, poor memory, reduced attention, and slowness of thought. Whilst much of the earlier literature presented conflicting results, more recently the theory that there is slowed …
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Feigning Cognitive Deficits on Neuropsychological Evaluations: Multiple Detection Strategies
… frequently stand to gain in some manner if neurocognitive dysfunction is diagnosed. As a result, neuropsychologists are customarily asked to test for neurocognitive feigning during the assessment. The current study employed an analogue design with a clinical comparison group to examine the …
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Chronic Olanzapine Treatment Eliminates Cognitive Deficits Produced by Neonatal Quinpirole Treatment.
… the effects of chronic olanzapine treatment on cognitive performance and neurochemical function in a rodent model of schizophrenia. Animals were neonatally treated with quinpirole, a dopamine D<sub>2</sub> receptor agonist, or saline. Quinpirole treatment produces an increase of dopamine …
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NOVEL APPROACHES TO MODELING AND TREATMENT OF COGNITIVE DEFICITS IN NEUROPSYCHIATRIC DISEASES
Kognitive Defizite und Beeinträchtigungen höherer Hirnfunktionen sind die meist belastenden Aspekte neuropsychiatrischer Erkrankungen (z.B. Elvevag & Goldberg, 2000). Bis jetzt existieren keine zufriedenstellenden Therapien zur Behandlung kognitiver Störungen bei neuropsychiatrischen Erkrankungen …
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TREM1-Mediated Neuroinflammation is Critical to Global Ischemia-Induced Neurodegeneration and Cognitive Deficits.
… for learning and memory, ultimately leading to cognitive impairments. While therapies for cardiac arrest primarily focus on restoring blood flow and cardiac function, there are currently no effective treatments that address the global ischemia-induced neurological deficits. Understanding the …
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Interleukin-6 trans-signaling: implications for neuroinflammation and cognitive deficits in the aged
… response, as well as prolonged behavioral and cognitive deficits when compared to adults. This is attributed to a population of activated or “primed” microglia that produce excessive amounts of pro-inflammatory cytokines, such as interleukin (IL)-6. The over production of IL-6 during aging is …
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HIV-1 INFECTION OF NEURAL STEM CELLS RESULTS IN COGNITIVE DEFICITS THROUGH ADULT NEUROGENIC MODULATION
… accelerated aging, and most notably, neurocognitive deficits. HIV-1 associated neurocognitive disorders (HAND) denote a spectrum of neurocognitive deficits that are either asymptomatic in nature (asymptomatic neurocognitive impairments, ANI), mild to moderate in intensity (mild …
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An Investigation of Cognitive Deficits Related to Surgery for Glioblastoma using a Computerised Assessment Tool
Thesis Abstract An Investigation of Cognitive Deficits Related to Surgery for Glioblastoma using a Computerised Assessment Tool - Rohitashwa Sinha Glioblastoma, the most aggressive type of primary brain cancer, causes abysmal survival rates and high risks of cognitive deficit to its sufferers. …
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The Role of Cognitive Deficits in Vulnerability to Depression and Anxiety: An Individual Differences and Neuroimaging Approach
… display complex symptom presentations. While cognitive deficits have been demonstrated in meta-analyses of currently depressed individuals (Snyder, 2013), a number of questions remain as to the role of cognitive deficits in depression. Given ongoing debates about whether the FDA should approve …
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Linking WRP/srGAP3 to the Cognitive Deficits in 3p- Syndrome and Its Role in the Regulation of Dendritic Filopodia Formation
… system, and what role its loss may have on cognitive functions.</p><p>To assess these roles, biochemical studies were performed to characterize the way in which WRP's novel IF-BAR domain interacted with lipid membranes. Additionally, WRP's role in regulating neuronal function was assessed …
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Effects of Natural Antioxidants on Motor and Cognitive Deficits in an Animal Model of Aging and Obesity and Dopaminergic-Like SH-SY5Y Cell Line
… age is associated with increased motor and cognitive deficits. Loss of balance, falls, hip fractures, and poor memory all contribute to a decline in the quality of life of the aging population. While ongoing research is making advances to find therapeutic interventions for neurodegenerative …
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Cognitive Function in the Alcohol Addiction Treatment Population
… alcohol abuse has been linked to several cognitive deficits, such as problems with spatial processing, decreased executive functioning, impaired verbal fluency, poor working memory, response inhibition, and social problems such as aggression and social deviance. In order for patients to …
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Using Multiple Biological Markers to Measure Sickle-Cell Disease Severity and Cognitive Risk
… complications including brain perfusion deficits and tissue infarction, which can lead to cognitive deficits early in life. Timely assessment and detection of these deficits is critical for effective intervention. Biological measures of disease severity may serve as clinical markers of …
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Evaluating Cognitive Changes in Patients Receiving Outpatient Alcohol Treatment
… health concerns, neurological changes, and cognitive deficits. Research has shown that some of these neurologic and cognitive deficits can improve over time following detoxification and abstinence; however, the exact nature or timeline of this recovery process has not been established. The …
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An Investigation of Short-Term Memory Functioning in a Neurodevelopmental Rat Model of Schizophrenia
… characterized by positive, negative, and cognitive symptoms. Cognitive deficits affect one’s learning and memory due to a dysfunction in the brain, inhibiting a normal functioning life. The self-medicating hypothesis states that ninety percent of people with schizophrenia smoke, because …
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Validation of an animal model of cognitive dysfunction associated with schizophrenia. Development and validation of the novel object recognition task using behavioural manipulations and psychotomimetic dosing regimens to induce cognitive deficits of relevance to schizophrenia in hooded-Lister rats.
… with continual and treatment resistant cognitive deficits which are now recognised as a core feature of the disease. The aim of the studies reported in chapter 3 were to establish a set of objects with equal preference in the NOR (novel object recognition) test. Furthermore, the …
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