Global ETD Search

Development of Graphical Models and Statistical Physics Motivated Approaches to Genomic Investigations

Lagisetty, Yashwanth, <p>0000-0001-7364-4630</p>2023

… GeneEMBED, to model the total effect of protein coding variants in various genes across a molecular network of genetic interactions. Given a population of disease and healthy individuals, GeneEMBED systematically evaluates the relative contribution of a gene to disease. The associations are …

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Characterization of aberrantly spliced hsNotch1 variants induced by non-coding mutations in chronic lymphocytic leukaemia (CLL)

Guo, MinUniversität Ulm

ulm-diss Repository record for Characterization of aberrantly spliced hsNotch1 variants induced by non-coding mutations in chronic lymphocytic leukaemia (CLL) (opens in a new tab)

Molecular mechanisms underlying avian metabolic variation: a genomic approach

Stager, MariaUniversity of Illinois at Urbana-Champaign2014

… In the second, I instead characterize coding mutations that occur on the timescale of generations. I show that differences in the mitochondrial sequences of the genes encoding the machinery of cellular metabolism could result in canalized differences in whole-organism aerobic …

uiuc Repository record for Molecular mechanisms underlying avian metabolic variation: a genomic approach (opens in a new tab)