Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"coactivator complex"”.
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Isolation and Characterization of Estrogen Receptor- Interacting Proteins
… receptor associated protein (TRAP)/Mediator coactivator complex, which interacts with ERα and ERβ both in unfractionated nuclear extracts and in purified form equally efficiently. Although some of other interacting proteins displayed subtype specificity, the main focus of the work was to …
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Second-site inhibitors of the estrogen and androgen hormone receptors
… efforts to directly disrupt the nuclear receptor/coactivator and the nuclear receptor/DNA interactions, and to increase degradation of receptor through binding of small-molecules at non-traditional binding sites. Due to the essential nature of these interactions for estrogen and androgen receptor …
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Molecular Genetic Analysis of Spinocerebellar Ataxia Type 7 and a Further Study on the RNA Interference Analysis
… supposed a subunit of a transcriptional coactivator complex (called TFTC or STAGA) that has histone acetyltransferase activity. So far effective treatmentsof polyglutamine diseases containing SCA7 have not yet been developed. Inhibition of mutated allele expression provides a direct …