Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"coREST complex"”.
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Characterisation of oncogenic pathways driving the pathogenesis of prostate cancer
… demonstrated that TBX2 interacts with CoREST complex members LSD1 and ZNF217 and ChIP qPCR confirmed TBX2 shRNA reduced ZNF217 recruitment to E-cadherin and NDRG1 promoters. In accordance, targeting the LSD1/ZNF217 interaction via an allosteric LSD1 inhibitor phenocopied TBX2 knockdown …
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Analysis and suppression of mutant sel-12 in Caenorhabditis elegans
… is found to be an integral component of the CoREST transcriptional co-repressor complex. Further analysis of the other spr genes revealed that SPR-1 is the C. elegans homolog of the human CoREST protein, which is also a component of the CoREST complex. Based on the physical interaction of …
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Simulating biochemical physics with computers
… the external PLP!L-dopa aldimine (the Michaelis complex). How the intrinsic properties, solvent effects as well as the enzyme environment control the shift of the equilibrium is discussed. Afterward, the free energy profiles for the decarboxylations of the external aldimines both in water and in …