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Showing 1 to 2 of 2 for “"clusterin expression"”.
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Studien zur Regulation der Clusterin-Expression in der MCF-7- und MDA-MB-231-Mamma-Karzinom-Zelllinie
The secretory form of the clusterin protein (sCLU) consists of a 38-kDa glycosylated alpha- and beta-chain, which arise from the cleavage of the 65-kDa sCLU precursor protein. sCLU is produced in inflamed epithelia and apoptotic cells and inhibits apoptotic cell death. In human breast carcinomas, …
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Regulation of the Insulin-like Growth Factor 1-Secretory Clusterin Expression Axis in Genomic Instability and Cell Stress
Secretory clusterin (sCLU) is a pro-survival factor that is up-regulated in human tumors and after exposure to cell stress. Understanding the regulation of sCLU expression in cancer, and after exposure to therapeutic agents, could reveal new therapeutic targets for cancer treatment. A DNA damage …