Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"closed-loop insulin delivery"”.
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Closed-loop insulin delivery in adults with type 1 diabetes
… 1 diabetes with currently available methods of insulin delivery is challenging. Aggressive regimens carry an increased risk of hypoglycaemia, particularly overnight. Both alcohol consumption and exercise predispose further to low glucose levels. The demands are even greater in pregnancy where, …
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Investigation into reliability and performance of an implantable closed-loop insulin delivery device
An implantable closed-loop insulin delivery device (INsmart device) containing a glucose responsive gel has been developed within the INsmart research group, over a period of 10 years, to mimic pancreas. In this thesis, the reliability and performance capability of the INsmart device was studied …
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The impact of closed-loop insulin delivery on glucose control in children and young people with type 1 diabetes mellitus: Longer-term benefits across the paediatric age-spectrum
… and is characterised by a deficiency of insulin caused by immune-mediated destruction of pancreatic beta cells in genetically predisposed individuals. Despite increasing technology use to manage type 1 diabetes, most children struggle to meet treatment guidelines for target glycated …
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The Artificial Pancreas in Children and Adolescents with Type 1 Diabetes: Bringing Closed-Loop Home
… ongoing development of more physiological insulin preparations, recent advancements in insulin pump technology and more accurate blood glucose monitoring, in clinical practice it remains challenging to achieve normoglycaemia whilst reducing the risk of hypoglycaemia, particularly in young …
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Glycaemic control in pregnancies complicated by type 1 diabetes
… 1 diabetes. I present the first home studies of closed-loop insulin delivery in this population. The aim of these studies was to assess the feasibility, efficacy, and utility of overnight and then day-and-night closed-loop insulin delivery in pregnant women with type 1 diabetes. The overnight …
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Bio-Inspired and Nanotechnology-Enabled Drug Delivery for Diabetes and Brain Cancer
Nanotechnology-enabled drug delivery systems, inspired by biological processes, were developed to overcome current treatment challenges facing diabetes and cancer patients. Two different systems were developed. The first system, an implantable closed-loop insulin delivery device, utilizes …