Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 9 of 9 for “"clinical sequelae"”.
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TEMPOL and Insulin Resistance: A study of the underlying mechanisms behind changes in glucose metabolism, lipid accumulation and cellular stress
… to treat insulin resistance or its downstream clinical sequelae. It was hypothesized that TEMPOL, a nitroxide, could suppress diet-induced insulin resistance through its anti-inflammatory and antioxidant properties. To explore this hypothesis, C57BL/6 mice were treated with a high-fat diet to …
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A detailed study of persons admitted to the spinal unit of conradie hospital, Pinelands, Cape, during 1985.
… areas. 0 The levels of the cord lesions and the clinical sequelae are analysed, and while Tetraplegia and Paraplegia are well described in all series on spinal cord injuries, this series is unique in the large number of Brown-Sequard type lesions (36, or 12,7% of all patients) that exist, …
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Risking Reproduction: Reproductive Health Among Women With Sickle Cell Disease
… disease (SCD) is a condition with a complicated clinical sequelae, accompanied by a myriad of health complications, unremitting, extreme pain, and frequent hospitalizations. The purpose of this study was to explore the meaning and lived experiences of reproductive health and health care among …
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Evidence of Water to Human Transmission of Aeromonas Hydrophila: Critical Role of Quorum Sensing in Bacterial Virulence & Host Response
… in humans. A large number of water and clinical Aeromonas isolates were molecularly finger-printed and our data provided the evidence of successful colonization and infection of humans with particular strains of certain Aeromonas species after consumption of water. Further, we delineated …
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Characterization of polymicrobial infections in macaques with chronic cranial implants and evaluation of alternative antimicrobial strategies
… which can occasionally progress to clinical sequelae of meningitis and brain abscesses. In this thesis, we first examined aerobic and anaerobic bacterial species colonizing CRCs using both traditional culture-dependent methods and 16S microbiota culture-independent methods. We …
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Disease mechanisms and markers of progression in cerebral small vessel disease
… feature of SVD that are strongly correlated with clinical sequelae, and I further tested whether brain lesion volume can regress over time. In part II I investigated the role of two novel pathophysiological mechanisms (inflammation and the permeability of the blood-brain barrier), and their …
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Calcium-binding system in bile
Gallstones are a common clinical problem associated with significant morbidity and mortality whether managed conservatively or by surgery. Since a sizeable proportion of the resources of the community is spent dealing with the clinical sequelae of these stones, much interest has been focused on …
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Genetic and functional studies in inherited platelet disorders
… the whole exome sequencing (WES) and associated clinical data for 500,000 UK Biobank (UKB) participants. The first part of this thesis reports on the interrogation of UKB data to determine, for the first time, the effect sizes on platelet parameters of reported rare pathogenic and likely …
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Epidemiology and clinical investigation of West Nile Virus encephalitis in Houston, Texas
… provides us with a better understanding of the clinical aspects of a virus that is likely to continue to circulate in the United States, and allows us to identify populations at risk for encephalitis and death.