Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 609 for “"clinical outcomes"”.
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Immune biomarkers predicting clinical outcomes for major trauma patients
… as a predictive biomarker of late MODS and poor clinical outcome. This study aims to analyse the trends of 7 subsets of T lymphocytes; CD3+, CD4+, CD8+, CD25BRI, CD4+FOXP3+, CD25BRIFOXP3+, and CD127LOWFOXP3+ following major trauma, in the hopes of utilizing these as predictive biomarkers in the …
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Improving clinical outcomes in rheumatoid arthritis: a patient centred approach
… to address three inter-related aspects of clinical care. Firstly, identifying critical challenges for providing patient-centred care. Secondly, defining outcomes important to patients like fatigue and pain and concomitant fibromyalgia. Finally, examining temporal changes in the RA …
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Clinical Outcomes after Endovascular Management for Non-maturing Native Arteriovenous Fistula
목적: 미성숙 자가동정맥루에서 시행한 혈관 내 치료의 성공률과 개통률을 평가하고 개통률에 영향을 미치는 인자들을 알아보고자 한다. 대상과 방법: 2006년 1월부터 2011년 3월까지 불충분한 자가동정맥루 성숙으로 혈관 내치료를 시행 받은 141명을 대상으로 후향적으로 진행하였다. 혈관 내 치료 후 개통률은 Kaplan-Meier techinique을 통해 추정하였다. 환자의 연령, 성별, 동반이환 질환, 동정맥루 종류, 동정맥루 형성 기간, 협착부위의 개수, 협착 정도, 우회정맥 치료 여부에 따른 1차개통률의 차이를 …
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Impact of Kras/Nras Mutational Heterogeneity On Clinical Outcomes In Colorectal Cancer
… NGS results, we described the prevalence and clinical impact of atypical (not in current guidelines) and low rMAF <em>RAS</em> mutations (RAS MAF by the MAF of the mutated gene with the highest allele frequency to normalize for tumor content. Functional annotation of 113 <em>RAS</em> mutations …
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Genetic Predictors of Clinical Outcomes In Non-Small Cell Lung Cancer Patients
… susceptibility to the diseases as well as clinical outcomes, such as survival and recurrence. We aimed to identify genetic prognostic markers for non-small cell lung cancer (NSCLC), a major (85%) subtype of lung cancer, and also in other subgroups. With the fast evolution of genotyping …
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Nutritional Status and Clinical Outcomes of Residents Admitted to a Nursing Home
… residents admitted to nursing homes and adverse clinical outcomes in those residents after four weeks. Methodology A descriptive, correlational design utilizing medical record data was used to examine the relationship between nutritional status and adverse clinical outcomes of weight loss and …
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The first anatomically shaped meniscus prosthesis: Improving biomechanical performance and clinical outcomes
Contains fulltext : 332599.pdf (Publisher’s version ) (Closed access)
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Influence of gut function, on SIRS and clinical outcomes in surgical patients
… dysfunction remains an unrecognised clinical entity in day to day clinical practice hence it is possible many patients are inadequately managed resulting in poorer clinical outcomes. Recognising gut failure and early initiation of gut directed therapies may influence clinical …
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Performance-Based Quality Specifications: The Link between Product Development and Clinical Outcomes
… product development functions supported by clinical pharmacokinetic (PK) and pharmacodynamic (PD) data. Largely, the importance of variance and covariance in product and patient attributes is poorly understood. The existence of PK/PD diversity among myriad patient sub-populations further …
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The psychosocial and clinical outcomes of surgery for Thyroid Eye Disease (TED)
… surgery and whether any demographic, clinical or psychosocial factors can predict which patients might benefit from this surgery. One hundred and twenty three adults with TED were recruited from Moorfields Eye Hospital (MEH), London. Clinical measurements were taken by the clinical …
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Endovascular cerebral aneurysm treatment : one year radiological and 4-year clinical outcomes
Includes bibliographical references.
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Impact of a Digital Pharmacy on Medication Adherence, Clinical Outcomes, and Healthcare Utilization
… of a digital pharmacy on medication adherence, clinical outcomes, and healthcare utilization for those with chronic diseases. A secondary objective was to assess the relationship between usability of the digital pharmacy and medication adherence. Methods: At baseline, demographic and …
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The Association between Depression, Anxiety and Clinical Outcomes for Type 2 Diabetes Mellitus
… the impact of depression and/or anxiety on clinical outcomes of diabetes, including glycosylated hemoglobin (HgA1c), blood glucose, blood pressure, total cholesterol, weight and LDL among patients with incident type 2 diabetes mellitus (T2DM).</p> <p>Method: A retrospective cohort study …
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Evaluating the Impact of the Guatemalan Nursing Program on Staff, Organizational, and Clinical Outcomes
… and impact on staff, organizational, and clinical outcomes. Staff and organizational outcomes were evaluated using a before and after one group design often used in program evaluation. The clinical outcomes were evaluated using a control site comparison but no randomization and was …
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An integrative bioinformatics approach to characterize molecular landscapes and clinical outcomes in acute leukemias
Acute leukemias are biologically and clinically heterogeneous hematologic malignancies. This dissertation examines this heterogeneity at three levels: population-based disease patterns, RNA-seq-based molecular classification, and developmental interpretation. First, nationwide German cancer …
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Association of cardiovascular and musculoskeletal biomarkers with clinical outcomes in chronic obstructive pulmonary disease.
… to reliably identify or predict these common clinical outcomes. The aim of this research was to identify and evaluate the predictive value of existing and novel biomarkers for COPD, and determine if and how these biomarkers can predict the longer-term clinical outcomes using electronic health …
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Sex-Specific Head Impact Exposure in Rugby: Measurement Considerations and Relationships to Clinical Outcomes
… or the accumulation of lower severity impacts. Clinical changes that can result from concussion include an elevated symptom presentation and changes in gait, or an individual's walking pattern. It is not well understood if similar deficits result after an accumulation of subconcussive impacts. …
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Minimally invasive adrenalectomy for pheochromocytoma: a systematic review of clinical outcomes compared with open surgery
Το φαιοχρωμοκύττωμα είναι σπάνιος νευροενδοκρινικός όγκος του μυελού των επινεφριδίων, με ιδιαίτερη κλινική σημασία λόγω της παραγωγής κατεχολαμινών και του κινδύνου σοβαρής περιεγχειρητικής αιμοδυναμικής αστάθειας. Η χειρουργική επέμβαση αποτελεί τη μόνη οριστική θεραπεία. Ανέκαθεν, η ανοικτή …
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Clinical Outcomes Associated with Speech, Language and Swallowing Difficulties Post-Stroke – A Prospective Cohort Study
… speech, aphasia, dysphagia), risk factors, and outcomes post-stroke (i.e. length of hospital stay, degree of physical disability according to the Modified Rankin Scale [mRS], functional level of oral intake according to the Functional Oral Intake Scale [FOIS], dehydration, weight loss, …
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The economic and clinical outcomes and policy implications of gene expression profiling in breast cancer care
… breast cancer patients are recommended by clinical guidelines to receive adjuvant chemotherapy to prevent disease progression and increase survival. However, low-risk patients may be experiencing the side effects of chemotherapy, with no corresponding benefit, which may also lead to …
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