Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 222 for “"clinical outcome"”.
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Transcatheter Aortic Valve Implantation: Risk Assessment and Clinical Outcome
… following TAVI. Methods: In this work we studied clinical outcome, prediction of 30-day mortality and acute kidney injury and late renal dysfunction following TAVI. In paper I and IV, a comparisons to propensity score matched patients undergoing AVR were made. Results: The 30-day mortality …
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Immune biomarkers of clinical outcome in patients with major trauma
… is postulated to follow a ‘two-hit’ course, with clinical outcomes being dictated through a complex interplay between cascades of systemic pro-inflammatory and compensatory anti-inflammatory responses (SIRS and CARS). The desired outcome, homoeostasis, is the resultant balance between the two …
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Electrocardiographic predictors of clinical outcome in ST-elevation myocardial infarction
… the experimental part (Studies I, II, III) and clinical register-based retrospective studies (Studies IV and V). Closed-chest porcine model of myocardial infarction (MI) was used in the experimental part. Occlusion of left descending artery (LAD) lasted 40 minutes and was followed by …
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Clinical Outcome in the Surgical Intervention of Congenital Muscular Torticollis
… facial asymmetry angles (HFAA and LFAA) in the clinical photograph were used to measure facial asymmetry. Postoperative improvements in HFAA and LFAA were evaluated in each age group, after grouping the patients by age. Patients were divided into 2 groups according to the postoperative head tilt …
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Influence Of Previous Cesarean Section On Clinical Outcome Of Medication Abortion
… pregnancy test at follow-up. Demographic and outcome data was collected from patient self-report pre-procedure intake and follow-up questionnaire forms. Parity regardless of delivery type increased the risk of failure (p=0.0422) but previous Cesarean section did not (p = 0.6141). Duration of …
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Novel Serum Biomarkers For Lung Cancer Early Diagnosis and Clinical Outcome
… tremendous efforts made, serum biomarkers with clinical utility for lung cancer early detection and clinical outcome prediction are still lacking. Metabolic alterations have been recognized as an emerging hallmark of cancer. We aimed to investigate the metabolic changes associated with lung …
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Switching State Space Modeling via Constrained Inference for Clinical Outcome Prediction
In clinical settings, timely and accurate prediction of adverse patient outcomes can help guide treatment decisions. While deep learning models such as LSTMs have demonstrated strong predictive performance on multivariate clinical time series, they often lack interpretability. To address this gap, …
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Major traumatic injury : serum cytokine biomarkers as predictors of poor clinical outcome
… markers as a potential predictor of poor clinical outcome in major trauma. The study is a continuation of a research project with a larger cohort of 200 patients selectively recruited from Central Manchester Foundation Trust (CMFT) and Salford Royal Foundation Trust (SRFT).The aim of the …
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Clinical outcome and Predictive factors of Coronary aneurysm after Percutaneous Coronary Intervention
… findings may be related with adverse clinical events because recent DES registry data showed CAAs took mostly favorable clinical courses with continuous dual-antiplatelet therapy (Ahn et al., 2010) although poor clinical outcomes including in-stent restenosis and stent thrombosis after …
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Clinical Outcome and Prognostic Factors of Acute Symptomatic Intracranial Vertebrobasilar Artery Dissection
… a cause of stroke in East Asian populations, its clinical course and treatment method are not yet established. The purpose of this study was to retrospectively evaluate treatment methods, clinical outcome, and prognostic factors of patients with VBD. Two hundred seventy-two patients (M:F=173:99; …
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PATIENT SIMILARITY NETWORKS-BASED METHODS FOR MULTIMODAL DATA INTEGRATION AND CLINICAL OUTCOME PREDICTION
… vast array of diverse health data. This includes clinical data, radiological and digital pathology images, molecular data, and information from wearable devices and smartphones. Such developments have ushered the field of biomedicine into the era of "Big Data", presenting unique challenges in data …
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Investigating cytokine biomarkers as early predictors of poor clinical outcome following major trauma
… their use as a predictive biomarker of poorclinical outcome. The data from the analysis of 80 major trauma patients show averaged IL-6 7and IL-10 levels to decrease in major trauma patients from Day 1 to Day 5 post-admission(IL-6 p=0.000; IL-10 p=0.000), while the trends for IL-4 and IL-12 …
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CRITICALLY ILL PATIENTS WITH COVID-19 PNEUMONIA: PATHOPHYSIOLOGY, IMPACT OF VACCINE, AND CLINICAL OUTCOME.
… quickly worldwide evolved in a pandemic. The clinical spectrum of the disease ranges from asymptomatic conditions to the development of acute respiratory distress syndrome (ARDS) with need of intensive care unit (ICU) admission. The present manuscript focuses on three main topics. The first …
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ANALYZING CLINICAL PRESENTATION, SERVICE UTILIZATION, AND CLINICAL OUTCOME OF FEMALE SEXUAL MINORITY COLLEGE STUDENTS
Researchers examining clinically-relevant trends for sexual minority women have found evidence of psychological distress and greater utilization of mental health services compared to heterosexually-identified women. However, the results of many research studies with this population have …
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Nutritional intake, systemic vascular function and clinical outcome in Bolivian highlanders with Chronic Mountain Sickness
… CMS is not understood and likely multifaceted, clinical symptoms of the disease disappear by descending to a lower altitude. CMS is characterized by exaggerated chronic arterial hypoxaemia, excessive erythrocytosis(EE) that can lead to myocardial failure and stroke, both recognised as the most …
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Investigating Interleukin – 8 and TGF Beta as early biomarkers predicting poor clinical outcome in major trauma
… could be exploited as biomarkers to predict poor clinical outcomes and second phase deaths in major trauma. IL-8 as a pro-inflammatory cytokine and TGF-β as a pleiotropic cytokine with a potent regulatory activity were investigated for their potential as early biomarkers. The availability of such …
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Comparison of clinical outcome after revascularization versus conservative treatment in patients with borderline fractional flow reserve measurements
… severity of coronary artery stenosis and for clinical decision of treatment strategy. Many studies have shown that FFR measurement <0.75 is specific for ischemia, but there is a controversy about whether we need to intervene the lesion of FFR measurement 0.75-0.80 or not. The objective of this …
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Exploring topological data analysis in gene expression data topology-driven biomarker discovery and clinical outcome prediction in oncology
… to tackle two key challenges in cancer research: clinical outcome prediction and biomarker discovery. In this study, we employ Weighted Gene Topological Data Analysis (WGTDA) to extract topological features from gene expression data, which serve as prognostic biomarkers for cancer classification, …
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INTRA-TUMORAL INFILTRATION OF GZMKHIGH CD8+ T EFFECTOR MEMORY CELLS IS ASSOCIATED WITH POOR CLINICAL OUTCOME IN NON-METASTATIC COLORECTAL CANCER.
As with most solid tumor malignancies, CRC possess more than one major histological subtype that likely generate disparate immune responses. The heterogeneity in the immune cell response to CRC highlights the need to develop novel immune diagnostics that could predict the risk of disease relapse …
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The Influence Of Host Genetics And Different <i>Mycobacterium tuberculosis</i> Strains On Macrophage Functions And Clinical Outcome Of Tuberculosis Disease
… activities influence TB presentations and clinical outcomes. Many studies have shown host and bacterial genetics are important factors in TB susceptibility and progression. I hypothesized that an impairment of macrophage phagocytic function, under the influence of genetic factors, may help …
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