Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 153 for “"clinical laboratory sciences"”.
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Quantitative analysis of K-ras mutation in urine as an indicator of disease status in patients with stage II or higher colorectal cancer
… (M.S.)--Michigan State University. Department of Clinical Laboratory Sciences, 2008
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Implementation of a Clinical Laboratory Science Internship Program at Dominican University of California
<p>The demand for California licensed clinical laboratory scientists (CLS) is rapidly growing due to increased CLS retirement, a high CLS vacancy rate, and decreased California approved training programs. With only 13 approved training programs in California, hundreds of qualified applicants are …
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A Comparative Study of the Pathology and Pathophysiology of Severe Malaria in a Non-Human Primate Model
… the Armed Forces Research Institute of Medical Sciences in Bangkok, Thailand, compounded with data and material from a series of prospective experimental studies, the work in this thesis sought to fully characterize and describe the pathology and pathobiology of the P. coatneyi/Rhesus macaque …
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A Model for International Clinical/Biomedical Science Programs
… and mutual credentialing systems for laboratory professionals. It also examined a potential transatlantic student exchange program for laboratory sciences students. The study addressed key problems confronting the laboratory profession, such as workforce shortages, mobility issues, and …
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Developing/testing a new approach for assessing rapid visual identification of hematological cells using principles of visual cognition: a health science education study
… (WBC) identification skills used in the field of Clinical Laboratory Sciences (CLS). A dual format exam was administered to both novices (students) and experts (laboratory professionals). Format 1 was similar to current assessment formats, simply presenting a series of single WBC images for …
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Demographic Characteristics and Academic Measures as Predictors of Success on the American Society for Clinical Pathology (ASCP) Medical Technologist Certification Examination
… of success for the American Society for Clinical Pathology Board of Registry Medical Technologist Certification Examination (Certification Examination) Total Score and six Subscores and to find predictive models with relevance to an ethnically and racially-diverse student population.</p> …
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Retrospective review of gunshot injuries at Salt River mortuary, Cape Town, Western Cape
The use of firearms to inflict fatal trauma is a social, economic, and public health concern globally. In South Africa, firearm-related injuries (FRIs) have become the leading cause of unnatural death. Despite this, few studies have investigated the demographic, geographic and temporal distribution …
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Opinions and practices of medical specialists concerning medical genetic services at the Pietersburg and Mankweng academic teaching hospitals in the Limpopo Province
… the province and the provincial National Health Laboratory Service does not have a genetics diagnostic laboratory. Thus, there are currently no medical genetic services available or outreach programmes within either the public or private healthcare systems in Limpopo. Any patients requiring …
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Diagnostic yield of tuberculosis investigations on bone marrow biopsy samples in HIV positive patients at Groote Schuur Hospital
… participants who had TB diagnosed from another clinical site were bone marrow TB culture negative. TB treatment was confirmed in 11/33 participants recruited prospectively. One trace positive GeneXpert® MTB/RIF Ultra result on peripheral blood was detected. All TB cultures on bone marrow …
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The characterization of Lowe Syndrome in a South African cohort
… OCRL (NM_000276.4 c.2615delC) gene. We present a clinical and molecular characterization of an extended multiplex family of three affected boys with Lowe Syndrome and describe a novel variant, predicted to be pathogenic, in the OCRL gene. This is to the best of our knowledge the first description …
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Characterizing the cellular latent reservoir of HIV-1 and the effect of immune activation on characteristics of the reservoir
… women and subsequently determining whether clinical or immune measures influence characteristics of the latent reservoir of HIV-1. T cell activation and the levels of soluble inflammatory cytokines in plasma were determined in forty-six women in the CAPRISA 002 Acute infection cohort. …
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The role of pulmonary innate and adaptive immune responses to helminth infection
Immunity to nematode infections requires a host T helper 2 (Th2) response promoted by epithelial cell driven IL-33 induction of cytokine secretion of Interleukin (IL)-4, 5 and 13 by a range of immune cells including innate lymphoid cells type 2 (ILC2s) and CD4+ T cells. This induces effector …
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The role of Lymphoblastic leukemia 1 (Lyl1) in Mycobacterium tuberculosis (Mtb) infection
Lymphoblastic leukemia 1 (Lyl1) is a well-studied transcription factor known to exhibit oncogenic potential during various forms of leukemia. Since its discovery in 1989, many reports have been published describing its relationship with cancer as well as demonstrating its function during …
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Human myeloid cell and innate lymphocyte responses to mycobacterial vaccination or infection
We investigated immune responses beyond conventional T cells in the context of BCG vaccination and tuberculosis disease.
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The role of pulmonary innate and adaptive immune responses to helminth infection
Immunity to nematode infections requires a host T helper 2 (Th2) response promoted by epithelial cell driven IL-33 induction of cytokine secretion of Interleukin (IL)-4, 5 and 13 by a range of immune cells including innate lymphoid cells type 2 (ILC2s) and CD4+ T cells. This induces effector …
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Investigating the views and expectations of pregnant women who undergo genetic counselling for age-related risk of aneuploidy
Background: Pregnancy at advanced maternal age (AMA) is associated with an increased risk of aneuploidy. In the Western Cape's public health sector maternal age alone is widely used to screen women for high risk of pregnancies affected by aneuploidy. The weekly pregnancy counselling clinic (PCC) at …
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The role and host-directed targeting of long non-coding RNAs in macrophage polarization during Mycobacterium tuberculosis infection
In 2020, the World Health Organization (WHO) reported 1.5 million tuberculosis (TB)- associated deaths and an incidence of 10 million new cases. The causative, Mycobacterium tuberculosis (Mtb), evades host immune responses by skewing macrophage polarization towards a less microbicidal alternative …
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In vivo and in vitro regulation of plasminogen activator inhibitor type-1
The human leukaemic cell line, K562 can be induced to differentiate along the megakaryoblastic pathway by the addition of phorbol myristate acetate and, during this process, the cells switch from producing a mixture of active tissue plasminogen activator (t-PA) and urokinase (u-PA) to producing …
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Whole-genome transposon mutagenesis to elucidate the genetic requirements for vitamin B12 biosynthesis and assimilation in mycobacteria
Comparative genomic analyses have identified an altered capacity for cobalamin biosynthesis as a critical step in the evolution of the pathogenic Mycobacterium tuberculosis Complex strains from a common environmental ancestor. However, resolving the full gene complement involved in the complex, …
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The knowledge of basic genetic terms and available terminology in the South African Sotho languages
The use of indigenous terms during a genetic counselling session has the potential to foster a better understanding between a genetic counsellor and patient. However, it is unknown if there are specific terms for commonly used English genetic terminology in the South African indigenous languages. …
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