Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 655 for “"clinical implications"”.
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Comorbid opioid dependence and chronic pain: Clinical implications
… What are the clinical characteristics and treatment outcomes associated with comorbid chronic pain in ORT patients?<br/>(2) Does the patient-attributed direction of the causal relationship in the development of opioid dependence and chronic pain identify two …
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Change of Uric Acid and its Clinical Implications
"요산은 주로 뇌-심혈관계 위험인자를 많이 가지고 있는 사람들에서 증가되어 있고, 최근 뇌-심혈관계 질환의 새로운 위험인자로 대두되고 있는 대사증후군에서도 종종 증가되어 있으며, 뇌-심혈관계의 발생이나 예후를 예측할 수 있는 인자라고 알려져 있다. 하지만 요산은 우리의 몸에서 매우 강력한 항산화제이다. 한편 우리 몸 산소를 가장 많이 소비하고 산화손상의 주요 기질인 지방산이 풍부한 뇌는 근본적으로 산화손상에 취약하다. 게다가 이러한 산화손상을 일시적으로 받을 수 밖에 없는 급성 뇌경색에서 자유유리기가 폭발적으로 나오는 급성 …
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Arterial Calcification and the Clinical Implications on Stent Function
… setting. Arterial calcification, observed clinically with mild to severe levels, was investigated to determine the impact on stent performance. The analysis demonstrated that arterial calcification does significantly affect stent function, resulting in a 60% increase in logarithmic strains …
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Wellbeing Impacts and Clinical Implications of Near-Death Experiences
… when working with NDErs. It adds to the clinical literature as well as the parapsychology, thanatology, and health literature.
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Experimental Analyses of Rule-Following: Methodological and Clinical Implications
… thesis investigated the methodological and clinical implications of rulefollowing behaviour. The research program comprised eight experimental studies, including the match-to-sample methodology and the use of radiant heat apparatus. Chapter 1 provides a review of the available literature on …
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Frontal Plane Pelvic Drop in Runners: Causes and Clinical Implications
<p>Running is becoming an increasingly popular sport; however, runners have a high rate of injury and are therefore often treated in the orthopedic or sports medicine setting. One current focus of these patients' treatment is gluteus medius muscle (GM) strengthening and gait retraining, with the …
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Evaluation and Clinical Implications of Biomarkers of Electronic Cigarette Use
… used to verify patient’s smoking status in clinical settings. However, cotinine is a biomarker that is selective for all nicotine-containing products and does not distinguish between tobacco cigarette smoking and e-cigarette use. The second biomarker commonly used in clinical trials is …
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The molecular landscape of cutaneous melanoma and its clinical implications
… has traditionally relied on the examination of clinical and pathological features, however it has become clear that traditional staging may fall short in accurately assessing an individual patients’ risk. There is therefore a need for robust prognostic biomarkers capable of identifying truly …
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Defining The Role of Egfr Acetylation In Cellular Processes: Clinical Implications
… expression of EGFR. The evidence from pre-clinical or clinical trials demonstrated significant enhancement of therapeutic efficacy by using such a combination therapy. Our <em>in vivo</em> study also demonstrated that the combination of SAHA and TKI for the treatment of breast cancer …
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Clinical Implications of Binaural Interference: A Systematic Review of the Literature
… with binaural interference, to identify clinical implications of this body of literature, and to answer two research questions:</p> <p>1) Does the literature describe changes in susceptibility to binaural interference with age?</p> <p>and</p> <p>2) Does evidence suggest whether binaural …
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Exploring Clinical Implications of Consensual Non-Monogamy: A Proposed Intake Assessment Tool
… are often socially stigmatized and clinically pathologized. The existing research on consensually non-monogamous individuals indicates, despite negative assumptions, those who engage in consensually non-monogamous relationships demonstrate psychological well-being, physical health, …
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Molecular chaperones and telomerase expression profiles and inhibition: Clinical implications for Glioma
… of glioma and has thus far shown evidence of clinical activity in patients with melanoma, breast and prostate cancer. With this in mind, the primary focus of this thesis was to evaluate the association between hsp90a expression in glioma versus the normal brain cell lines and tissues. Results …
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Clinical Implications of HIV-1, HSV-2 Co-infection and Opportunities for Intervention
… progression to opportunistic infection or clinical AIDS, but not with increased HIV viral load. Some evidence suggests that HSV-2 disease activity is associated with increased HIV viral load and decreased CD4 counts. Study 2 compared rates of CD4 count change by HSV-2 status (Focus …
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Monogenic Defects of the Type I Interferons Signaling Pathway in Humans: Molecular and Clinical Implications
… time, growing appreciation for the extent of subclinical infections, that is, infections where the germ is detectable in its host without causing overt disease, and the Mendelian inheritance patterns of some infectious diseases have reinvigorated the study of the human genetic basis of infectious …
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Bisexuality, Biphobia, and its Effects on Sexual Identity, Religious Identity and Mental Health: Examining Clinical Implications
… impact mental health and other conditions for clinical attention? (4) How can understanding bisexuality and biphobia influence clinical treatment to promote protective factors and improve mental health disparities for bisexual people? Limitations, clinical implications, and recommendations for …
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Your Attention Please: Neural Networks, Individual Differences, and Clinical Implications of Attentional Control in the Human Brain
… models of attention and discuss possible clinical implications.
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Discovering the biological and clinical implications of modulating glucocorticoid action using metabolomic profiling of human plasma samples
… identify because ofthe non-specificity of their clinical and biochemical features which are also poorlycorrelated with levels of circulating steroids. The lack of reliable biomarkers forglucocorticoid action makes it challenging to determine precise therapeutic needsof patients with GC-deficient …
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An Investigation Into The Mineral And Mechanical Properties Of The Canine Intervertebral Disc And Its Clinical Implications
Intervertebral disc disease is a very common problem in dogs. The disease causes pain and different degrees of neurological damage which can result in paralysis and leads to the death of many dogs annually. The disease is intimately associated with disc degeneration and calcification, but the …
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