Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 243 for “"clinical application"”.
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Optical coherence tomography: evaluation and clinical application
… with regards to its potential within routine clinical practice. A number of investigations were performed to fuffil this evaluation. Tests were carried out to experimentally measure the system's resolution and the accuracy and precision of measurements made from the OCT scans. A number of …
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Development of a Mathematical Model of Renal Function for Clinical Application
<p>This model describes the orthoiodohippurate (OIH) distribution and clearance in the renovascular system. The model is described by five compartments: the blood, left and right kidneys, bladder and the red blood cell compartment. Data for these compartments, except the RBC compartment, are …
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Measurement of cyclic nucleotides in human sperm: experimental and clinical application
The biochemical state of human sperm is critical for fertilisation potential, yet no convenient or reliable methods are available to assess essential second messengers. Cyclic nucleotides (cAMP and cGMP) play a crucial role as signalling molecules for capacitation, motility, and acrosome reaction …
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Development of the Clinical Application of miRNA with Proregenerative Effect on the Heart
… infarction. Objective: As a first step towards clinical translation, in this study we assess the efficacy of the pro-regenerative miR-199a after myocardial infarction, delivered using an AAV vector in a pig model of ischemia-reperfusion and as a synthetic RNA molecule after a single intracardiac …
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CLINICAL APPLICATION AND PROGNOSTIC VALUE OF COMPUTED TOMOGRAPHY EXAMINATION IN FOALS DIAGNOSED WITH HEMATOGENOUS OSTEOMYELITIS
… However, the association between CT findings and clinical prognosis is lacking in the literature. The objectives of this thesis were to; Provide a detailed resource of descriptive data of foals diagnosed with osteomyelitis, to compare findings obtained by conventional imaging methods and CT, and …
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Sensory integration: analyses of patterns of dysfunction and clinical application with children with mild disabilities
… (LD). Controversial issues regarding the application of SI are discussed, SI research is critiqued, and the current practice of occupational therapists using SI is described.Models of SI dysfunction based on scores of children on the Sensory Integration and Praxis Tests (SIPT; Ayres, 1989) …
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Acute heart failure: Scottish temporal trends in hospitalisation, outcomes and clinical application of natriuretic peptides
… - has the potential to improve the practical clinical utility of NT-proBNP testing. Overall, my thesis findings suggest that improvements in the prevention and treatment of heart failure have had progressive and sustained effects on the incident AHF hospitalisation and outcomes at the …
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Clinical Application of S.salivarius 24SMBc in the Prevention of Recurrent Otitis Media in Paediatric Age
ABSTRACT (Italian) Introduzione. Recentemente, lo studio della microflora orale ha suscitato molto interesse al fine di sviluppare una batterioterapia mirata alla prevenzione e/o trattamento delle infezioni delle alte vie respiratorie. La cavità orale ospita alcune specie di batteri benefici come …
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Measurement of calprotectin (S100A8/S100A9) and S100A12 in serum: method development, analytical validation, and clinical application
… an existing method to ensure its suitability for application in a new assay or devising a suitable method by integrating the expertise and experience of the personnel undertaking the task of method development. Assay validation process for commercially available serum immunoassay kits is necessary …
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PERSPECTIVES ON THE CLINICAL APPLICATION OF LEWIS ANTIGENS IN PANCREATIC CANCER: TOWARDS A PERSONALIZED TUMOR MARKER STRATEGY
Background. Carbohydrate antigen 19.9 (CA19.9) is used as a tumor marker in gastrointestinal cancers, assuming that it is produced by cancer cells. Recent data has suggested that, in pancreatic ductal adenocarcinoma (PDAC), elevation of CA19.9 could depend on its reabsorption in the bloodstream. No …
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Development and Clinical Application of Techniques for the Image Processing and Registration of Serially Acquired Medical Images
In many magnetic resonance imaging (MRI) applications, it is necessary to compare regions of interest (ROIs) on different images of the same patient. This comparison is often made difficult when the scanned tissue volume is not in exactly the same three dimensional location each time. Registration, …
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Studies of a restricted signature of circulating miRNAs as non-invasive biomarker in glioma: from the molecular function to the clinical application
Gliomas are diffusely growing brain tumours and challenging cancers for diagnosis and treatment. The identification of genetic and epigenetic markers has led to an integrated diagnosis, composed of a histological diagnosis, and a molecular profile of the tumour. Among the key genetic events, …
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Development and clinical application of assessment measures to describe and quantify intra-limb coordination during walking in normal children and children with cerebral palsy
… walking. The researcher was motivated by her clinical experience as a paediatric physiotherapist. She observed that the pattern of lower limb coordination differed between normal children and those with cerebral palsy. Many of the currently used interventions did not appear to influence this …
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Clinical Application of Prognostic Factors and Their Integration in a Risk and Time to Treatment Assessment Scale for Treatment-Naive B-CLL Patients // Клинично приложение на прогностичните фактори и интегрирането им в скала за оценка на риска и времето до лечение, при нелекувани пациенти с В-хронична лимфоцитна левкемия
Хроничната лимфоцитна левкемия е една от най- честите левкемии при възрастни, характеризираща се с изключително променлив клиничен курс и различен изход на заболяването, дефинирани от множество фактори свързани със сложните патогенетични процеси протичащи в неопластичните клетки. Темата на …
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New minimally-invasive laser treatment in orthopaedics on spinal deformations and bone tumours
… extensive investigations were carried out for a clinical application in orthopaedics. With a focus on laser tissue interactions, this work covers a broad range of different applications from cw to femtosecond laser systems. Throughout this work, the emphasis was put on laser tissue interaction …
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Real-time image-based cell identification
… an indispensable task of biomedical research and clinical application. During the last decades, much attention was given to molecular characterization, and many cell types can now be identified using established markers that bind to cell-specific antigens. The required staining process is a …
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COMPARATIVE STUDIES OF DIFFERENT SYSTEM MODELS FOR ITERATIVE CT IMAGE RECONSTRUCTION
… One of the key factors that limit the clinical application of an iterative reconstruction algorithm is the high computational cost which mainly depends on the system model. This thesis can serve as the basis for the acceleration study and will have a direct impact on development of fast …
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Psychological Acculturation, Coping Strategies, and Mental Health Among Asians and Asian Americans
… satisfaction. Its implications for research and clinical application are discussed.
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