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Showing 1 to 3 of 3 for “"classification of protein domains"”.
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Exploring the function and evolution of proteins using domain families
Proteins are frequently composed of multiple domains which fold independently. These are often evolutionarily distinct units which can be adapted and reused in other proteins. The classification of protein domains into evolutionary families facilitates the study of their evolution and function. In …
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Bioinformatische Identifikation von Domänenunterschieden bei Parasit und Wirt am Beispiel der Malaria
… zu nutzen. Hierzu müssen zunächst Proteindomänen und wichtige regulatorische RNA Elemente erkannt werden. Dies geschieht für regulatorische Elemente in Nukleinsäuren am Beispiel von Iron Responsive Elements (IREs) in Staphylococcus aureus, wobei sich solche Elemente in viel …
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Organised Chaos: defining different degrees of intrinsic disorder by molecular dynamics methods
Intrinsically disordered proteins (IDPs) and regions (IDRs) are defined as proteins, or proteins’ regions, that lack a stable 3D structure. The nature of the IDP(R)s amino acid residues and their sequence prevents these systems from folding. IDPs and IDRs are ubiquitous in biology, playing many …