Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 401 for “"clamp"”.
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Clamp–On Magnetic Energy Harvesting
Large-scale deployment of low-power sensing and computing units call for unique power management solutions to overcome the inconvenience, costs, and waste problems associated with batteries. Energy harvesting offers an exciting solution to the battery problem, enabling circuits that can power …
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High-voltage ESD PNP clamp simulation and design
In this work high-voltage Electrostatic discharge (ESD) PNPs are studied through TCAD simulation and device measurement. PNPs for three different voltage classes, 16 V, 65 V, and 100 V, in a 0.5-µm Bipolar CMOS DMOS (BCD) technology are used as the context for the study. The PNPs are varied in …
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Comparative Studies of Processivity Clamp Loader ATP Site Function
<p>DNA replicases utilize ring-shaped sliding clamps to ensure polymerase processivity. An ATP-dependent clamp loader topologically links the clamp around DNA in a multi-step mechanism. Clamp loaders are ring-shaped pentamers of AAA+ subunits. The pentamer complex contains 3-4 ATP sites, each …
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Processive bio-hybrid catalysts based on the T4 clamp protein
Contains fulltext : 72127.pdf (Publisher’s version ) (Open Access)
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Characterization of cardiac IKs channel gating using voltage clamp fluorometry
… work develops a voltage sensor assay, voltage clamp fluorometry, to measure movements of the voltage sensor and explore changes to the voltage sensor induced by KCNE1 and disease-causing mutations. Chapter 1 validates this technique using mutagenesis to ensure the assay reports on voltage …
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Development of planar patch clamp with potentiometric calcium ion-selective electrode
… the flow of ions in and out of the cell. Patch clamp technology has been the proven standard for fundamental studies of ion channel activities. However, the technique has some basic limitations: low throughput, time consuming nature of its process, need of highly skilled personnel and inability …
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Carton Clamp Methodologies and the Effects on Load Containment and Retention
<p>ABSTRACT</p> <p>Carton Clamp Test Methodologies and the Effects on</p> <p>Load Containment and Retention</p> <p>Tyler Don Blumer</p> <p>A carton clamp is an alternative device for moving packages and material. Instead of using iron tines like that of a conventional forklift, a carton clamp uses …
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Silicon nanopore patch clamp device for measuring single ion channel activity
… the Nobel Prize for their invention of the patch clamp, which is based on the formation of a high resistance seal between a glass micropipette and a cell membrane. This transformative method allows low noise recording of current arising from single ion channels or from an entire cell and has no …
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Active-clamp PWM converters: design-oriented analysis and small-signal characterization
… addresses issues related to the use of an active clamp (ACL) circuit in high-frequency PWM converters with an electrical isolation. Existing design guidelines and design trade-offs for the ACL in forward and flyback converters are reviewed, and specific properties of both circuits that are caused …
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Molecular and Biochemical Analyses of a Three-Subunit Euryarchaeal Clamp Loader Complex
… requires two processing factors, sliding clamp and clamp loader, to direct rapid and accurate DNA replication. In eukaryotes, the ring-shaped sliding clamp, proliferating cell nuclear antigen (PCNA), encircles double-stranded DNA within its central hole and tethers the DNA polymerases onto …
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Design of Active Clamp for Fast Transient Voltage Regulator-Down (VRD) Applications
… and current control buck converter, active clamp has a lot of the advantages for the transient response. With proper design, active clamp can generate a very high bandwidth since there is no compensator needed in the control loop. Since active clamp bypasses inductor and is connected …
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Der Einfluss lokaler Ionenkonzentrationsänderungen in Membrannähe bei Voltage-Clamp-Messungen am Modellsystem Skelettmuskel
… auf den Stromverlauf bei Voltage-Clamp Experimenten quantitativ zu untersuchen. Als Modellsystem wurde der Skelettmuskel gewählt, wobei zwischen Ca2+-Strömen und K+-Strömen unterschieden wurde, die exemplarisch als Anwendungsbeispiel für physiologisch wichtige Ionenströme …
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Two-Electrode Voltage Clamp (TEVC) Based Scanning Ion Conductance Microscopy: New Methodology and Validation
… microscopy, confocal microscopy, and patch clamping. A key feature of SICM is its non-invasive scanning ability. The ability to scan samples without coming making contact allows for more robust research in biology. Current SICM techniques call for a one electrode probe, but in this research …
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LNA-clamp-PCR zum sensitiven Nachweis von Punktmutationen im Rahmen der Entwicklung eines Darmkrebsfrüherkennungstests
… Arbeit wurde dazu die Methode der LNA-clamp-PCR (locked nucleic acid) etabliert. Die Bewertung der erzielten Anreicherung erfolgte über das relative Detektionslimit. Zur Bestimmung des Detektionslimits wurde die Schmelzkurvenanalyse von Hybridisierungssonden eingesetzt; diese wurde im …
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Die Kinetik des heteromeren 5-HT3-Rezeptors: Untersuchungen mit Patch-Clamp-Technik und Computersimulationen
Der 5-HT3-Rezeptor gewinnt zunehmend pharmakologische Bedeutung, z.B. hinsichtlich der Wirkmechanismen von Antidepressiva. Diese wirken u.a. als 5-HT3-Rezeptor-Antagonisten oder hemmen die präsynaptische Serotonin-Wiederaufnahme. Darüber hinaus werden 5-HT3-Antagonisten in der Therapie des …
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CLAMP : application merging in the ECOIN context mediation system using the context linking approach
… benefits of merging and presents the design for CLAMP, a tool that facilitates ECOIN application merging.
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Nucleic acid clamp-mediated transcriptional and translational modulation of oncogenes via the stabilization of G-quadruplexes
… Therefore, we developed a novel nucleic acid clamp (NA-clamp) based strategy, which takes advantage of both the highly specific complementary base pairing capability of nucleic acids and the length variation of nucleic acid structures, in order to stabilize individual G4s with high …
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