Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 162 for “"cirrhosis"”.
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The epithelial-mesenchymal transition of hepatocyte in liver cirrhosis
Liver cirrhosis is characterized by hepatic dysfunction with extensive accumulation of fibrous tissue in the liver. Even though the number of hepatocytes seems to be enough to maintain liver function, hepatic failure is one of the main causes of death in the patients with liver cirrhosis. The role …
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Cirrhosis-Induced Defects in Innate Puemonary Defenses Against Streptococcus Pneumoniae
… pneumonia is very high in those with cirrhosis, even when they receive intensive care support and appropriate treatment. However, the defects in host defense responsible for the increased morbidity and mortality from pneumococci in these patients have not been clearly elucidated. In …
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Portal hypertension in cirrhosis and its associated pulmonary vascular disorders
… with mortality increasing year on year. Cirrhosis, through portal hypertension (PH), leads to complications, including pulmonary vascular disorders, portopulmonary hypertension (PoPH), and hepatopulmonary syndrome (HPS). PoPH and HPS are poorly characterised and associated with a worse …
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A four-year study of cirrhosis at Groote Schuur hospital
… Africa. A significant number of patients with cirrhosis present for the first time at Groote Schuur Hospital with decompensation and a diagnosis of cirrhosis is made on the basis of association of signs of liver failure, portal hypertension, radiological features consistent with cirrhosis with …
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Effects of Early Cirrhosis on Hepatic Vascular Resistance in the Rat
… in the liver is a common symptom of established cirrhosis of the liver. This investigation measured changes in resistance during induction of cirrhosis, to determine whether the increase in vascular resistance might be part of the mechanism by which cirrhosis develops. Procedure. Early cirrhosis …
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Entecavir Therapy for Patients with Hepatitis B Virus-Related Decompensated Cirrhosis
목적: 엔테카비어는 HBV에 강력한 항바이러스 효과가 있으며 내성이 드물게 발생한다. 비대상성 간경변증 환자에서 엔테카비어의 장기 치료 효과에 대한 연구 결과는 많지 않다. 이에 저자들은 B형 간염 바이러스에 의한 비대상성 간경변환자를 대상으로 엔테카비어 치료 효과와 엔테카비어 효과를 예측할 수 있는 인자를 알아보고자 하였다. 대상 및 방법: 2006년 11월부터 2011년 1월까지 아주대학교 병원에 내원한 만성 B형 간염으로 인한 비대상성 간경변 환자 중 6개월이상 엔테카비어 치료를 받은 45명을 후향적으로 조사하였다. 대상 …
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Drinking Behavior and Sodium Appetite in an Animal Model of Hepatic Cirrhosis
No abstract prepared.
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Studies of Prognosis and Nutritional Intervention in Liver Cirrhosis and Liver Transplantation
… in the literature exist with regard to PEM in cirrhosis. This thesis aimed to address some of these issues: the prognostic utility of markers of PEM; the therapeutic benefit of a specialised immunonutritional supplementation in the peri-OLT setting; and whether PEM returns to normal in the long …
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Efficacy of Entecavir in Patients with Hepatitis B virus-Related Decompensated Liver Cirrhosis
"배경/목적: 엔테카비어는 강력한 항 바이러스 효과와 적은 내성 발생률로 만성 B형 간염 환자에서 치료제로 사용되고 있다. 엔테카비어는 비대상 간경변 환자들에게도 안전하게 사용될 수 있는 치료제로 추천되나, 비대상 간경변 환자에서 치료 효과에 대한 연구보고는 드물다. 이에 저자들은 B형 간염에 의한 비대상 간경변 환자를 대상으로 엔테카비어 치료 효과를 알아보고자 하였다. 연구대상 및 방법: 2006년 11월부터 2009년 9월까지 아주대학교 병원에 내원한 만성 B형 간염으로 인한 비대상 간경변 환자 중 6개월 이상 …
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THROMBUS GENERATION UNDER FLOW CONDITIONS IN PATIENTS WITH CIRRHOSIS AND THROMBOCYTOPENIA: THE CIRTAS-STUDY
Background: Thrombocytopenia is a hallmark of cirrhosis, however its effect on the bleeding risk remains uncertain due to a rebalance of hemostasis. Traditional coagulation tests, such as platelet count, prothrombin and activated thromboplastin time, fail to capture the complex interplay of pro- …
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Quality of Life Is Associated with Survival in Patients with Cirrhosis and Hepatocellular Carcinoma
The general metadata -- e.g., title, author, abstract, subject headings, etc. -- is publicly available, but access to the submitted files is restricted to UT Southwestern campus access and/or authorized UT Southwestern users.
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Quality of Care in Patients with Cirrhosis and Ascites, Hepatic Encephalopathy or Spontaneous Bacterial Peritonitis
… in real world clinical practice in patients with cirrhosis and ascites, hepatic encephalopathy (HE), or spontaneous bacterial peritonitis (SBP).</p> <p>Methods: A retrospective cohort analysis of the UPMC EMR database (2009-2014) with access to full outpatient and limited inpatient data was …
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HEPATIC DIFFERENTIATION OF HUMAN AMNIOTIC EPITHELIAL CELLS AND IN VIVO THERAPEUTIC EFFECT ON ANIMAL MODEL OF CIRRHOSIS
HUMAN AMNIOTIC EPITHELIAL CELLS (HAECS) HAVE BEEN TOUTED AS AN IDEAL CANDIDATE FOR HEPATOCYTE DERIVATION. AFTER IN VITRO HEPATIC DIFFERENTIATION, HAEC-HEP CELLS SHOWED DIFFERENTIAL REGULATION IN GENES INVOLVED IN LIVER FUNCTION, CYP450 ACTIVITIES AND LIVER TRANSCRIPTION FACTORS. IMMUNOFLUORESCENCE …
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Prediction of Compensated Liver Cirrhosis by Ultrasonography and Routine Blood Tests in Patients with Chronic Viral Hepatitis
… the standard method for the diagnosis of liver cirrhosis in patients with chronic hepatitis. Because the liver biopsy is an invasive method, non-invasive methods have been used to diagnose compensated liver cirrhosis in patients with chronic hepatitis. The current study was designed to evaluate …
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Effect of autologous macrophage therapy in cirrhosis in response to individual immune reparative pathways: developing a novel therapy
BACKGROUND: Liver cirrhosis is the end stage of any injury process to the liver. Once established it inevitably progresses to complications such as portal hypertension, cancer and death. There is not cure for liver cirrhosis besides liver transplant. We face an unmet demand for treatment of this …
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Tracking of Transplanted Mesenchymal Stem Cells Labeled with Fluorescent Magnetic Nanoparticle in Liver Cirrhosis Rat Model with 3T MRI
"Purpose : Liver cirrhosis represents the end stage of chronic liver injury and the only therapeutic option for advanced liver cirrhosis is liver transplantation. As a new therapeutic approach, there have been many studies about the therapeutic effect of transplantation of bone marrow stem cells. …
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The relative roles of portal hypertension and of cirrhosis in the pathogenesis of pulmonary lesions associated with chronic liver disease
… and pulmonary abnormalities in patients with cirrhosis and portal hypertension. The role of portal hypertension in the pathogenesis of pulmonary abnormalities in patients with liver disease has not been defined. The present study was therefore undertaken to clarify this. Pulmonary function, …
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Senescence and the Innate Immune System
… increased hepatocyte expression of HLA-G in cirrhosis of all aetiologies. My hypothesis was that senescent hepatocytes are removed from healthy liver by the innate immune system, as in healthy wound healing, but that in chronic liver disease there is a failure of this response, leading to an …
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