Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 3 of 3 for “"circulating nucleic acids"”.
-
Genetic Evolution and Prognostic Determinants of Pancreatic Cancer On Longitudinal Liquid Biopsies
… use so called “liquid biopsies” in the form of circulating nucleic acids and exosomes as a strategy that is amenable to longitudinal, relatively non-invasive sampling. Circulating tumor DNA and circulating exosomes contain genetic cargo representative of the neoplastic cells from which they are …
-
Investigating mitochondria alterations in esophageal pathologies
… DNA (mtDNA) copy number from culture media and circulating nucleic acids from human serum samples. Active EoE patients exhibited elevated serum mtDNA levels and upregulation of mediators of mtDNA-associated inflammatory signaling. Furthermore, increased mitochondrial mass and accumulation of …
-
Monitoring trace levels of ctDNA using integration of variant reads
In patients with early-stage cancer, ctDNA detection rates can be low due to the presence of few or no copies of any individual mutation in each sample. Sensitivity may be increased by collecting larger plasma volumes, but this is not feasible in practice. Although cancers typically have thousands …