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Showing 1 to 4 of 4 for “"circulating blood cells"”.

  1. Mitochondrial function in sepsis - Temporal evolvement of respiratory capacity in human blood cells

    … response, including dysfunctional peripheral blood immune cells has been described as part of the septic syndrome. Mitochondrial dysfunction has been suggested to be a contributing factor in the pathogenesis of these alterations and restoration of mitochondrial function has been implicated as …

    lund Repository record for Mitochondrial function in sepsis - Temporal evolvement of respiratory capacity in human blood cells (opens in a new tab)

  2. Single-cell Protein-Transcriptome Atlas of Haematopoiesis across the Human Lifespan

    … the continuous production of stem and progenitor cells, which divide and mature to produce a wide variety of specialised circulating blood cells. Proper regulation of lineage decisions is key to ensure the right balance between the generation of differentiated cells and the maintenance of the …

    cambridge Repository record for Single-cell Protein-Transcriptome Atlas of Haematopoiesis across the Human Lifespan (opens in a new tab)

  3. Gene expression profiling of patients with Polycythaemia Rubra Vera using cDNA microarrays

    … for the human PRV-1 gene. Analysis of different blood parameters of these mice in a collaboration with the LMU in Munich revealed significant differences compared to wild-type littermates with respect to granulocyte counts and different factors involved in iron homeostasis. Overexpression of the …

    freiburg-diss Repository record for Gene expression profiling of patients with Polycythaemia Rubra Vera using cDNA microarrays (opens in a new tab)

  4. Development and validation of an in vitro human model of drug-induced vascular injury

    … with a high incidence. Affecting the heart, blood vessels and blood components, CV ADRs can lead to hypertension, heart failure, cardiac arrhythmias and thrombosis. The prompt identification of CV toxicity would reduce both the delay and cost of drug development and increase patient safety. …

    cambridge Repository record for Development and validation of an in vitro human model of drug-induced vascular injury (opens in a new tab)