Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 6 of 6 for “"chymase"”.
-
Expression, Purification, and Characterization of the Mast Cell Proteases Chymase and Cathepsin G.
… eicosanoids, and the serine proteases, tryptase, Chymase, and cathepsin G (CatG). These proteases are stored and released from mast-cell granules upon activation by antigen binding to IgE immunoglobulins on the cell surface or by direct injury. In this study, chymase and CatG were expressed as …
-
L'activité chymase de la mMCP-4 est impliquée dans la conversion de la BIG-ET-1 EN ET-1 (1-31) chez la souris in vitro
… (ECE). Une seconde voie alternative via la chymase mMCP-4, une protéase à sérine, produit un intermédiaire de 31 acides aminés, l'ET-1 (1-31), à partir de la Big-ET-1. Par la suite, l'ET-1 (1-31) subit une hydrolyse pour former l'ET-1 par l'endopeptidase neutre (NEP). Les souris dont le gène …
-
Studies of the renin angiotensin system in the human vasculature
… that the combination of enalaprilat and the chymase inhibitor, chymostatin (but neither agent alone), inhibited the response to AI in human resistance arteries. Thus, a dual pathway for AII generation exists in human arteries, probably mediated by ACE and chymase. Since the significance of …
-
Sphingosine-1-phosphate in mast cell-mediated allergic responses
… increased the numbers of mast cells expressing chymase. These mast cells have functional FcepsilonRI, and similar to skin mast cells that express both tryptase and chymase (MCTC), also express CD88, the receptor for C5a, and are activated by anaphylatoxin C5a and the secretagogue compound 48/80. …
-
Role of mast cells in women's health and disorders of the endometrium
… by steroids. Mast cell proteases tryptase and chymase were detected by RTPCR and immunohistochemistry in “full thickness” (uterine lumen to endometrial-myometrial junction) biopsies from women undergoing hysterectomy. In agreement with previous findings MCs were most abundant in the myometrium. …
-
EGFR deficiency results in defective hair follicle cycling, resistance to chemotherapy-induced alopecia, and cutaneous inflammation
… hair follicles including the mast cell proteases Chymase and Tryptase and class I and II MHC molecules, consistent with a role for both innate and adaptive immunity in cutaneous inflammation following asynchronous catagen. The mitotic regulators Rcc2 and Sfi1 were increased correlating with our …