Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 21 for “"chronic wasting disease"”.
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Landscape Ecology of Chronic Wasting Disease in Virginia, USA
Wildlife diseases often occur under quantifiable and consistent patterns, which can be understood to statistically predict their occurrence and spread across landscapes. Chronic wasting disease (CWD) is a neurodegenerative disease in the deer family Cervidae caused by a prion, a pathogenic and …
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Molecular ecology and hierarchical models elucidate chronic wasting disease dynamics
… scenario because a single gene codes for both a disease agent and a functionally constrained native protein. The prion precursor gene, Prnp, codes for the prion precursor protein, PrP, which is constitutively expressed as a native isoform within all mammals. Upon misfolding to the disease …
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Investigating genetic vulnerability to chronic wasting disease in endangered cervid taxa
Chronic wasting disease (CWD) is a transmissible spongiform encephalopathy (TSE). TSEs are a group of progressive neurodegenerative diseases caused by prions. Prions are misfolded infectious proteins with a stable altered structure that allows them to induce conformational changes in normal …
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Hunters' responses to chronic wasting disease: specialization, social trust, and perceived risk
Chronic wasting disease (CWD) is found in deer, elk, and moose in several states and provinces. CWD causes abnormal behavior, emaciation, and death in all infected animals. Although CWD has not caused human health problems, transmission to humans cannot be dismissed. Little is known about the …
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Timing recombinant prion protein conversion as a measure of prion activity in chronic wasting disease
Chronic Wasting Disease (CWD) is a fatal neurological disease affecting cervids caused by prions. Infected cervids shed the CWD prion in bodily fluids and excrement, contaminating the environment and creating an agricultural and ecological calamity. Preclinical antemortem CWD testing method is …
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Chronic wasting disease as a model for the development of risk communication using the mental models approach
<p>Using chronic wasting disease (CWD) as a model for risk communication development using the mental models approach, this dissertation examines: 1) how published CWD risk communications compare to expert recommendations; 2) whether the experts and members of relevant stakeholder groups agree upon …
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Soil PH and clay content associated with chronic wasting disease in white-tailed deer in northern Illinois
Soil is an important reservoir for chronic wasting disease (CWD) which is a prion disease that infects cervids through both direct contact with infected animals and contact with contaminated environments. I built a boosted regression tree model that accurately predicted (AUC = 0.954) the …
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Monitoring for Chronic Wasting Disease in Mule Deer and White-Tailed Deer at Wind Cave National Park: Investigating an Emerging Epizootic
Chronic wasting disease (CWD) has emerged as a disease of concern in cervid populations. Testing, transmission, and detection of CWD are areas of interest for managing populations of North American deer (Odocoileus). This dissertation addresses these areas with research from data collected on mule …
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Characterizing U.S. Agency Approaches to Cervid Carcass Disposal in the Context of Chronic Wasting Disease Management: A Multi-State, Mixed-Methods Analysis
Chronic wasting disease (CWD) prions are notoriously resilient infectious agents that can retain infectivity in environmental settings for extensive periods of time. Given their pronounced durability and evidence of widespread prion distribution across an array of host tissues, the carcasses of …
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Exploring Novel Immunodiagnostics for Prion Disease
Prion Diseases, or Transmissible Spongiform Encephalopathies (TSEs), are rapidly progressive and fatal neurodegenerative diseases of mammals. TSEs of global importance include Creutzfeldt-Jakob Disease (CJD) in humans, Chronic Wasting Disease (CWD) in cervids, and Bovine Spongiform Encephalopathy …
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Use of the Protein Misfolding Cyclic Amplification for food safety and drug discovery
<p>Prion diseases are fatal neurodegenerative disorders caused by the misfolding of the normal prion protein (PrP<sup>C</sup>) into its infectious form (PrP<sup>Sc</sup>). While the zoonotic potential of chronic wasting disease (CWD) remains uncertain, the presence of prions in food products raises …
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Landscape genetics and CWD in white-tailed deer
… and population structure in the context of chronic wasting disease transmission and spread. Chronic wasting disease is an infectious prion encephalopathy in cervids that is endemic to Colorado and Wyoming but has spread across the US within the last decade. Quantifying white-tailed deer …
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Metabolic Profiling of Prions In The Gastro-Intestinal Tract
… <p><strong>Abstract</strong></p> <p>Prion diseases, also known as transmissible spongiform encephalopathies (TSEs), are a group of debilitating neurodegenerative disorders that affect both humans and animals. They can be spread by horizontal transmission as seen in chronic wasting disease …
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Improving the genome assembly and annotation of the white-tailed deer (Odocoileus virginianus borealis)
… areas. The species is affected by infectious diseases such as chronic wasting disease, epizootic hemorrhagic disease, and bovine tuberculosis. Genomic resources facilitate the study of pathogens, host-pathogen interactions, host genetic variation, and behavior. Repetitive elements are …
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Movement and Association of White-Tailed Deer in Southwest Minnesota
… and estimating risk for transmission of chronic wasting disease. Furthermore, knowledge of neonate survival and cause-specific mortality provides important information regarding reproduction, sex ratios, and how preseason mortality rates affect deer harvest strategies. However, biologists …
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Individual-based modeling of white-tailed deer (Odocoileus virginianus) movements and epizootiology
… game mammals and potential reservoirs of diseases of domestic livestock, so diseases of deer are of great concern to wildlife managers. In many situations, models can be useful for integrating existing data, understanding disease transmission patterns, and predicting effects on host …
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Determining Impacts of Mountain Lions on Bighorn Sheep and Other Prey Sources in the Black Hills
… We also documented a relatively high rate of chronic wasting disease- (CWD) infected elk in 2 cougar (1 male; 1 female) diets (64%; 95% CI = 50.3–78.3%) and speculate that CWD infection likely increased elk predation risk. Annual lamb survival was 0.02 (SE = 0.01) with pneumonia (36%) and …
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Habitat Selection and Range Overlap of Moose and White-tailed Deer in the Boreal Plains of Saskatchewan
… forests, potentially facilitating northward disease spread (e.g., meningeal worm, chronic wasting disease). Targeted harvest of deer in overlap zones and travel corridors could help limit disease expansion and conserve native cervids. In conclusion, anthropogenic disturbance is promoting …
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ECOLOGY AND MANAGEMENT OF WHITE-TAILED DEER IN AN AGRICULTURAL LANDSCAPE: ANALYSES OF HUNTER EFFICIENCY, SURVEY METHODS, AND ECOLOGY
… Midwest, especially given the novel presence of chronic wasting disease in the region. My objectives were to: 1) examine the potential effects of weather and row-crop harvest on daily harvest of white-tailed deer by archery, and individual hunter variables (e.g., age, weapon preference, …
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