Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 52 for “"chronic liver disease"”.
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Platelet Function in Dogs with Chronic Liver Disease
Background: Dogs with acquired chronic liver disease often have hemostatic derangements. It is currently unknown whether dogs with acquired chronic liver disease have decreased platelet function and alterations in von Willebrand factor (vWF) that may contribute to hemostatic abnormalities. …
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Factors associated with Liver Stiffness in Chronic Liver Disease
"목적: Tansient elastography는 간탄성률을 측정하여 간섬유화 및 간경변증을 예측하는 것으로, 비교적 정확하고, 비침습적인 방법이다. 그러나 최근 발표된 많은 연구에서 간탄성률은 만성바이러스간염환자에서 aminotransferase의 변화에 따라 영향을 받는 것으로 보고 되었다. 본 논문은 만성 간질환 환자를 대상으로 간탄성률 측정에 영향을 미치는 요인을 알기 위해 연구를 시행하였다 방법: 2005년 9월부터 2008년 9월까지 Tansient elastography와 간조직 검사를 시행한 만성 간질환 환자 …
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Epithelial cell plasticity in chronic liver disease (MASLD/NAFLD)
It has been proposed that liver regeneration in chronic liver disease, such as metabolic dysfunction-associated steatotic liver disease, previously known as non-alcoholic fatty liver disease, is driven by hepatocyte renewal in the early stages, but when hepatocyte proliferation is impaired due to …
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Molecular genetics of patatin-like phospholipase domain-containing 3 and chronic liver disease
Chronic liver disease is a major health burden worldwide. Major determinants of this condition are viral infections, alcohol abuse and obesity. Genetic background modulates the effect of damaging agents on the liver. The genetic variant rs738409 in the patatin-like phospholipase domain-containing 3 …
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Depression, Anxiety, Hazardous Drinking, Subjective Burden, and Rewards in Family Caregivers of Patients With Chronic Liver Disease
… reported by family caregivers of patients with chronic liver disease (CLD). Second, the investigator compared depressive and anxiety symptom levels, prevalence of hazardous drinking, rewards, and subjective burden reported by African Americans family caregivers with those reported by Caucasian …
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The relative roles of portal hypertension and of cirrhosis in the pathogenesis of pulmonary lesions associated with chronic liver disease
… of pulmonary abnormalities in patients with liver disease has not been defined. The present study was therefore undertaken to clarify this. Pulmonary function, including exercise testing, was evaluated in two groups of patients, 11 with portal hypertension due to cirrhosis and 10 with …
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Hepatitis C: A Perspective Through the Social Ecological Model
… global public health problem. The Center for Disease Control and Prevention (CDC) estimates that the Hepatitis C virus (HCV) affects 3.2 million Americans and 500 million people from a global standpoint (CDC, 2012). HCV contributes to significant morbidity and mortality with about 1 million …
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Impairments in signaling cascades mediating the progression of liver disease from chronic hepatitis to hepatocellular carcinoma in animal and human models
The most common risk factors for chronic liver disease, cirrhosis, and hepatocellular carcinoma (HCC) include chronic alcohol abuse and infection with hepatitis B (HBV) or hepatitis C (HCV) virus. Growing evidence from human studies and experimental models suggests that pre-degenerative and …
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A maternal high fat diet represses the expression of antioxidant defense genes and induces the cellular senescence pathway in the liver of male offspring rats
… increased risk of developing metabolism-related diseases in adult offspring, including chronic liver disease. The present study tested the hypothesis that maternal high fat diet leads to a decreased antioxidant defense capacity and causes cellular senescence in liver of adult offspring rats, …
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Unfolded Protein Response (UPR) Signaling in Hepatic Stellate Cells (HSC) as a Key Regulator of Liver Fibrosis
Liver cirrhosis is a leading cause of death worldwide, with the prevalence of cirrhosis on the rise. Cirrhosis is driven by various etiologies, including liver injuries from diabetes, obesity, metabolic disorders, and alcohol use. Central to the progression of chronic liver disease to cirrhosis is …
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Untersuchung der relativen Serum-Trisialotransferrin-Konzentration als möglicher prädiktiver Biomarker für hepatozelluläre Dedifferenzierung bei chronisch fibrogener Lebererkrankung
… AND AIM: The development of the virus induced chronic hepatitis is connected with the different types of hepatitis viruses. Hepatitis C-virus (HCV) and Hepatitis B-virus (HBV) can cause chronic hepatitis, whereas HCV in particular is related to the development of hepatocellular carcinoma …
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Der Einfluss von Fatigue auf die Lebensqualität von Patienten mit Leberzirrhose
… clinical impression that many patients with chronic liver disease develop fatigue symptoms. The aim of this work was therefore to determine its importance and its impact on quality of life, mental health and cognitive functioning in patients with cirrhosis without hepatic encephalopathy. 43 …
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Using Telemedicine To Optimize The Delivery Of Care In Patients With Liver Disease
<p>Chronic Liver Disease (CLD) is one of the top causes of morbidity and mortality globally. Among the spectrum of liver diseases, non-alcoholic steatohepatitis (NASH) is the most common cause of cirrhosis and one of the top reasons for a liver transplant. Patients with NASH end up with hepatic …
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The grapefruit flavonoid naringenin as a Hepatitis C virus therapy : efficacy, mechanism and delivery
… infection accounts for approximately 40% of chronic liver disease in the United States and results in an estimated 8,000-10,000 deaths annually. Simulations suggest that in the next decade morbidity and mortality associated with HCV infections will result in approximately 200,000 deaths and …
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Targeting LGALS3 to treat steatotic liver disease and hepatocarcinogenesis
Non-alcoholic fatty liver disease (NAFLD), recently renamed as Metabolic dysfunction-associated steatotic liver disease (MASLD), is the leading cause of chronic liver disease (CLD) and liver-related morbidity and mortality worldwide. NAFLD, characterized by hepatic fat accumulation and coexisting …
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Role of Ceramidase in Regulating Hepatic Lipid Metabolism and Whole Body Insulin Sensitivity
… obesity, the prevalence of non-alcoholic fatty liver disease (NAFLD), a newly emerging obesity-related disorder, has also been rising steadily. NAFLD is a chronic liver disease that ranges histologically from simple steatosis in its mildest form to non-alcoholic steatohepatitis (NASH) in the …
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Directed differentiation of endodermal cells from mouse embryonic stem cells
… an unlimited source of tissue for treatment of chronic diseases such as Type 1 diabetes and chronic liver disease. Various attempts have been made to produce cells that can serve as precursors for pancreas and liver. By using all-trans-retinoic acid, basic fibroblast growth factor, dibutyryl …
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Describing The Nutritional Outcomes Following Paediatric Liver Transplantation At A Tertiary Hospital In South Africa
Background: Nutrition in chronic liver disease is an important marker of post- liver transplant outcomes in children and is monitored judiciously pre-transplantation. There is a paucity of data on post-transplant nutritional outcomes, particularly in the developing world setting. Aim: To describe …
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The Prevalence of Comorbid Chronic Disease in Virginia's Adult Patient Population during the Years 2001 and 2004
Objective: Chronic disease comorbidities, on the rise in the U.S. and Virginia, represent a new challenge to the way medicine is practiced and prescribed. This descriptive study uses Virginia hospital discharge data to describe the prevalence and trends of chronic disease comorbidities present in …
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Expression Of Hepatitis C Viral Non-structural 3 Antigen In Transgenic Chloroplasts
… is the major cause of acute hepatitis and chronic liver disease and remains the leading cause of liver transplants (NIH). An estimated 180 million people are infected globally (WHO). There is no vaccine available to prevent hepatitis C. The treatment with antiviral drugs is expensive, …
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