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Showing 1 to 4 of 4 for “"chromosome fragmentation"”.

  1. The role of SYN1 in early Arabidopsis meiosis

    … Cytological analysis of syn1\(^{-/-}\) has shown chromosome fragmentation at metaphase I. To determine the basis of chromosome fragmentation in the syn1\(^{-/-}\), three double mutants were constructed. I have demonstrated that chromosome fragmentation in syn1 is AtSPO11-1-dependent. Moreover, I …

    birmingham Repository record for The role of SYN1 in early Arabidopsis meiosis (opens in a new tab)

  2. Identification and Characterization of Factors Involved in Sodium Selenite Toxicity

    … as a molecular read out, I took advantage of a chromosome fragmentation assay to detect SeL-mediated DNA damage. A new factor involved in SeL resistance is the high mobility group (HMG) protein Hmo1. As Hmo1 has been shown to interact with Topoisomerase 2 (Top2) to organize chromatin …

    sevilla Repository record for Identification and Characterization of Factors Involved in Sodium Selenite Toxicity (opens in a new tab)

  3. Study of mechanism of genetic death in Escherichia coli in response to A) dTTP starvation and B) combination of temperature sensitive defects in replication initiation and double strand break repair

    … a possible mechanism of replication-independent chromosome fragmentation observed in hyper-TLD mutants. The fourth chapter is a compilation of TEM images of E. coli cells undergoing TLD. As a comparison, we have also imaged E. coli cells treated with nalidixic acid, which kills the cells by …

    uiuc Repository record for Study of mechanism of genetic death in Escherichia coli in response to A) dTTP starvation and B) combination of temperature sensitive defects in replication initiation and double strand break repair (opens in a new tab)