Global ETD Search
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Showing 1 to 5 of 5 for “"chromosome 9p21"”.
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Hereditary risk factors for stroke in humans - Association studies with emphasis on familial and genotypic factors
… population was used. Paper IV: SNP rs4977574 on chromosome 9p21 was related to IS risk (OR=1.12; 95% CI: 1.04-1.20) and large vessel disease risk (OR=1.36; 95% CI: 1.13-1.64). This genetic effect of chromosome 9p21 on IS was however already known. None of the other 24 SNPs or compiled risk scores …
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Characterization of 𝘈𝘵𝘩𝘴𝘲1, an Atherosclerosis Modifier Locus on Mouse Chromosome 4:
… a coronary heart disease susceptibility locus on chromosome 9p21 identified by genome-wide association studies in humans. In this study we have used congenic mice that were previously constructed to isolate 𝘈𝘵𝘩𝘴𝘲1, an atherosclerosis susceptibility locus identified in a cross between MOLF/Ei and …
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Cardiovascular Risk Genes in Prevention and Treatment Response
… life-style-factors and the CVD-SNP rs4977574 on chromosome 9p21 were evaluated in 24944 MDC-subjects during 15 years follow-up. There were interactions between rs4977574 and smoking on incident CAD (P=0.035) and CVD-mortality (P=0.012). The risk conferred by rs4977574 in never-smokers (n=9642; …
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Genetic Variations in Type 2 Diabetes and Cardiovascular Disease: A Focus on Gene-Lifestyle Interactions and Mendelian Randomization
… traits related to the metabolic syndrome. The chromosome 9p21 genotype modified the association of vegetable and wine intake with the risk of CVD. Lower risk of CVD by higher vegetable intake was restricted to non-carriers of the 9p21 risk G allele (Pinteraction = 0.043), while wine consumption …
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Prognostic Significance of Chromosome 9p Deletion in Clear Cell Renal Cell Carcinoma
… (RCC) has been explored in several studies. Chromosome 9p deletion was reported as an independent prognostic factor in clear cell subtype (ccRCC). The findings from these studies initially appeared promising however they were of limited clinical applicability due to lack of standardisation of …