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Showing 1 to 3 of 3 for “"chromosome 11p13"”.
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Structural analysis of LMO2 for the development of a small molecule inhibitor
… LIM-only protein encoded by a gene located on chromosome 11p13 and was originally discovered through its activation due to specific chromosomal translocations in patients with T-cell acute lymphoblastic leukaemia (T-ALL). The specific chromosomal translocations occur with either the T-cell δ …
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CYCLIN D1 AND WILMS TUMOR TRANSCRIPTION FACTOR-1 (WT1): POTENTIAL DIAGNOSTIC AND THERAPEUTIC MARKERS IN SMALL ROUND BLUE CELL TUMORS OF CHILDHOOD
… kidney cancer Wilms tumor, is a gene located on chromosome 11p13, which encodes zinc-fingers protein characterized by multiple alternative isoforms, with important regulatory functions in cell growth and development. The protein Cyclin D1 (CD1), encoded by the CCND1 gene, belongs to the highly …
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Expressionskartierung des menschlichen Chromosoms 11p13
… geklärt. Des weiteren wurden Allelverluste auf 11p13 in Verbindung mit verschiedenen Tumoren (Lunge, Blase, Brust, Ovar) beobachtet, ohne daß die ursächlichen Gene hierfür beschrieben werden konnten. Eine Kartierung und anschließende Sequenzierung dieser Region dient als Grundlage für die …