Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 4 of 4 for “"chromosomal fragmentation"”.
-
Chromosomal Fragmentation in Escherichia Coli: Its Absence in mutT Mutants and Its Mechanisms in seqA Mutants
While studying mutT and seqA mutants, we discovered a contaminating bacteriophage We studied, sequenced, and identified the phage as phi80. We looked at three interesting phenotypes: modification of the phage DNA to protect against restriction enzymes, sensitivity of lysogens to UV damage, and the …
-
The iron-dependent cyanide and hydrogen peroxide co-toxicity in Escherichia coli and its catastrophic consequences for the chromosome
… of CN potentiation of H2O2 toxicity and its chromosomal consequences. We have found that the ability of CN to recruit iron from intracellular depots such as ferritin contributes to its potentiation of H2O2 toxicity, whereas the major stationary phase intracellular iron depot protein, Dps, can …
-
The role of recombinational repair in the mechanism of killing during thymine starvation in Escherichia coli
… cells were observed to accumulate chromosomal breaks and induce the SOS response, indicating chromosomal damages, but it is unclear if the chromosomal damage is the cause of lethality. The goal of this work is to elucidate the mechanism of thymineless death, by investigating if the …
-
Genome Rearrangements: Structural Inference and Functional Consequences
… time. We show how to correct for the effect of chromosomal fragmentation in sets of contigs. We apply our methods to data originating mostly in the 12-genome Drosophila project [15]. We compare ten Drosophila genomes with two other dipteran genomes and two outgroup insect genomes. For scaffolds, …