Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"chromatin silencing"”.
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DNA Damage responses in plant stem cells
… damage in plant stem cells, I identified several chromatin‐silencing mutants showing spontaneous PCD in the root meristem, and studied the link between transposon silencing and the ATM/SOG1 pathway. Finally, by characterising responses to Cre‐catalysed recombination in the shoot meristem, I …
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Molekularbiologische und Röntgenmikroskopische Charakterisierung der Heterochromatinproteine des Nematoden Caenorhabditis elegans
… wurde C. elegans für die Erforschung der Heterochromatinproteine verwendet. Durch Sequenzvergleich mit Genom von C. elegans ergaben sich zwei homologe Gene, welche für drei Proteine HP1.1, HP1.2 und HP1.3 kodieren. Das Ziel dieser Arbeit war eine vergleichende Analyse dieser Proteine durch …
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Transposable elements and the regulatory logic of hematopoietic differentiation
… of gene expression by transcription factors, chromatin modifiers and cis-regulatory elements is central to establish cellular identity and function. Understanding this regulatory logic is critical for deriving select cell types in vitro for translational applications. The human hematopoietic …
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Spatiotemporal modelling in biology: from transcriptional regulation to plasmid positioning
… FLC regulation involves an antisense-mediated chromatin silencing mechanism, where alternative polyadenylation of antisense transcripts is linked to changed histone modifications at the locus and altered expression. Mathematical model predictions of FLC transcriptional dynamics are validated by …
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piRNA-dependent transcriptional gene silencing during Drosophila oogenesis and embryogenesis
… is recruited and induces transcriptional gene silencing (TGS) by connecting to the general chromatin silencing machinery of the cell resulting in changes of the epigenetic chromatin state, thus shutting down transcription. However, whether Panx acts on its own or if other proteins are involved …
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Studies of the MYM-type zinc finger protein ZMYM3
… work, I identify several members of a putative chromatin-silencing complex as novel RNase H2B binding partners whose binding is impaired by each mutation in this cluster, including: HDAC2, a histone deacetylase, LSD1, a histone demethylase, CoREST, a co-repressor of transcription, TFII-I, a …
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Effects of 2ʹ-fucosyllactose on brain and cognitive development of intrauterine growth restricted piglets
… genes in SGA piglets were associated with chromatin silencing, DNA binding, nuclear chromatin, and the nucleosome; and down-regulated genes in SGA piglets were associated with KEGG pathways for measles, influenza A, hepatitis C, and herpes simplex infection. A main effect of diet revealed …
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Molekulare Analyse der differentiellen Funktionen von Linkerhiston Isoformen bei Caenorhabditis elegans.
… beobachtet.Es wurde herausgefunden, dass H1.1 am Chromatin-kontrollierten silencing von Genen in der Keimbahn beteiligt ist. Der cytologische H1.1 Phänotyp hat die größte Ähnlichkeit zur mes-3 Mutante gezeigt und war nur bei den Hermaphroditen zu beobachten.H1.4 ist für die Entwicklung der …