Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"chromatin associated RNAs"”.
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Native chromatin extraction and its structure analysis
Structure determines function. Properly ordered chromatin organization is fundamental for accurate regulation of gene expression inside eukaryotes. A native chromatin extraction method is developed based on solid phase reversible immobilization (SPRI) using magnetic nanoparticles as carriers. This …
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RNA in the nucleus: insight into location and biological function
… Currently used technologies to study RNA chromatin interactions pull down individual RNAs and sequence the associated DNA. However, it remains challenging to identify chromatin associated RNAs and their genomic target sites. In this thesis, I will describe MARGI-seq, a method to identify …
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UNCOVERING LNCRNA-CHROMATIN INTERACTIONS SHAPING HUMAN MONOCYTE TO MACROPHAGE DIFFERENTIATION
… non-coding transcripts, that can associate with chromatin and contribute to the regulation of genome organization and gene expression. However, the functional roles of most chromatin-associated RNAs, particularly long non-coding RNAs (lncRNAs), are still being elucidated, with new functions …