Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 21 for “"chorioallantoic membrane"”.
-
Discovery of Novel Mechanisms Regulating Cancer Extravasation in the Chorioallantoic Membrane Model
… novel cellular and molecular events. I used the chorioallantoic membrane of chicken embryos as a model system of extravasation as it provides an accessible and highly vascularized structure. The combination of the chorioallantoic membrane of chicken embryos, nanoscale flow cytometry, and confocal …
-
Development of the chick chorioallantoic membrane (CAM) xenograft model to study metastasis and angiogenesis in autophagy deficient osteosarcoma cells
… to an unpredictable prognosis. The Chicken Chorioallantoic Membrane (CAM) assay has emerged as a valuable tool, offering an easy, inexpensive and rapid alternative for direct visualisation of tumour development. This study aimed to design and optimise the CAM assay as a physiologically …
-
Development of the chick chorioallantoic membrane (CAM) model to assess tumour growth and drug response in osteosarcoma and bladder cancer
… This study aims to optimize and apply the chick chorioallantoic membrane (CAM) assay, an innovative, cost-effective in ovo model that allows visualisation of tumour growth in an in vivo-like environment while minimising animal suffering. While CAM studies have shown promise in osteosarcoma …
-
Localization of Calbindin-D<sub>28k</sub> in Extra-Embryonic Membranes of Two Oviparous Scincid Lizards.
… a variety of cells that transport calcium. The chorioallantoic membrane and yolk sac of oviparous squamate reptiles (lizards and snakes) transport calcium from the eggshell and yolk to the developing embryo. I used immunohistochemistry to localize calbindin-D<sub>28K</sub> expression in the …
-
Effect of local changes to shell permeability on the gas exchange of the avian embryo / by Kerstin Wagner.
… embryo's ability to match the perfusion of its chorioallantoic membrane to regional differences in shell conductance was investigated.
-
The role of prostaglandins, nitric oxide and oxygen in the ductus arteriosi of the pre-term chicken embryo (Gallus domesticus).
… non-ventilated lungs and towards the body and chorioallantoic membrane. I show that prostaglandins have a diminished role in maintaining chicken DA patency and nitric oxide inhibits oxygen induced contraction of the day 19 proximal DA in a time dependent manner. The pathways governing oxygen …
-
Pattern and Mechanism of Calcium Mobilization During Embryonic Development in a Viviparous Snake, <em>Virginia striatula</em>.
… and carbonic anhydrase II are expressed in chorioallantoic membrane, while yolk sac only expresses calbindin-D28k, coincident with the timing of calcium transport in embryos of <em>V. striatula</em>. Thus, the pattern of embryonic calcium accumulation in <em>V. striatula</em> is similar to …
-
The Effect of Mebendazole and RAN Mediated Pathways on Human Breast Cancer Cells
… and MCF7 breast cell lines. Finally, in vivo, a chorioallantoic membrane assay (CAM) was conducted to establish the antiangiogenic effect of Mebendazole. This study presents significant steps toward the clinical validation of Mebendazole as a combination therapy for reducing the invasion and …
-
Η ΒΙΟΣΥΝΘΕΣΗ ΤΩΝ ΒΑΣΙΚΩΝ ΜΕΜΒΡΑΝΩΝ ΩΣ ΒΙΟΧΗΜΙΚΟΣ ΔΕΙΚΤΗΣ ΤΗΣ ΑΓΓΕΙΟΓΕΝΕΣΗΣ
… ASSESSING ANGIOGENESIS. THE SYSTEM CHOSEN IS THE CHORIOALLANTOIC MEMBRANE (CAM) OF THE CHICK EMBRYO, AND THE METHOD IS BASED ON THE RATE OF BASEMENT MEMBRANE (BM) BIOSYNTHESIS DURING EMBRYOGENESIS. MORPHOLOGICAL EVALUATION OF ANGIOGENESIS WAS ACHIEVED BY COUNTING VASCULAR DENSITY OF THE CAM FROM …
-
First-order statistical speckle models improve robustness and reproducibility of contrast-enhanced ultrasound perfusion estimates
… (PDX) model of renal cell carcinoma (RCC) in the chorioallantoic membrane (CAM) of chicken embryos. The ultimate goal of the PDX model is to screen RCC patients for de novo sunitinib resistance. The analysis of the first-order speckle statistics of contrast-enhanced ultrasound cine loops provides …
-
Cultivation of Eimeria Dispersa in Bobwhite Quail Embryos
… of a tuberculin syringe. The allantoic fluid and chorioallantoic membranes were removed from inoculated eggs at 12-hour intervals from 1/2 through 10 days after inoculation. The chorioallantoic membranes were fixed in Zenker's fluid, stained with hematoxylin and eosin, and studied with …
-
Advanced in situ hydrogel assembly for guiding molecular release
… encapsulating VEGF was implanted on a chicken chorioallantoic membrane (CAM) to evaluate the neovascularization. Due to the spatiotemporal release of VEGF, the gel tubes significantly increased the density and diameters of blood vessels, compared to unfolded hydrogel patches and other …
-
The use of biomaterials for stem cell therapies to prevent myocardial damage post-infarct
… tissue regeneration. Using both a chick chorioallantoic membrane assay and a mouse model of MI, the following aims determined: 1) the vascularization potential of an MSC encapsulated patch, 2) the ability to deliver hydrogels containing pro-survival signals to the heart post-MI, and 3) …
-
Computational modeling-guided printing of proangiogenic hydrogel for vascular patterning
… the printed hydrogel was implanted on a chicken chorioallantoic membrane to examine vascularization in vivo. Specifically, the hydrogel implant was placed between two large pre-existing blood vessels, while making the direction of hydrogel strips in parallel with or perpendicular to the …
-
Modelling Embryonic Haematopoiesis Using In Vitro State-of-art Gastruloid Culture
… progenitors with OP9 cells. The chick embryo chorioallantoic membrane (CAM) assay and mouse transplantation experiments imply that the haemogenic gastruloid cells may possess engraftment capability. Single cell SMART sequencing data confirms that gastruloids have haematopoietic gene expression …
-
Surface Functionalisation of Metal-Organic Frameworks for Biomedical Applications
… as well as ex ovo using the Hen’s egg test-chorioallantoic membrane (HET-CAM) assay, showing increased biocompatibility, sustained release of the cargo, and enhanced performance compared to the free drugs at high concentration. Finally, a novel targeting mechanism based on lectin, a …
-
ANGIOTENSIN-(1-7): A NOVEL SMALL MOLECULE FOR THE TARGETED TREATMENT OF TRIPLE NEGATIVE BREAST CANCER
… by more than 50% in the developing chick chorioallantoic membrane assay, an effect attenuated by the Ang-(1-7) receptor antagonist [D-Pro7]-Ang-(1-7). Taken together, these results suggest that Ang-(1-7) inhibits angiogenesis in vivo through activation of an AT(1-7) receptor. Based on the …
-
Role of KATP channels in angiogenesis
… experimental approaches. In vivo, chick embryo chorioallantoic membrane (CAM) angiogenesis was similarly enhanced by the direct KATP channel activator SG-209 and by the polypeptides CNP or VEGF. Two KATP inhibitors, Glibenclamide and 5-Hydroxydecanoate (5-HD), abrogated both basal and …
-
Tissue Engineering von Fettgewebe durch Kultivierung humaner Präadipozyten und Endothelzellen
Die Korrektur von Weichteilgewebedefiziten gehört nach wie vor zu den Aufgaben und Herausforderungen in der Plastischen und Rekonstruktiven Chirurgie. Die Entwicklung von Tissue Engineering Fettgewebsäquivalenten, basierend auf der Transplantation von kultivierten, autologen …
Page 1 of 2