Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"chondrocyte death"”.
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Investigating the causes of chondrocyte death in septic arthritis
… explanation for the clinical results is that chondrocyte death could occur during septic arthritis. Chondrocytes are required to maintain healthy articular cartilage and in their absence degenerative change would be expected to accelerate. The predominant cause of damage appears to be related …
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The Influence of Maximal and Submaximal Cyclic Concentric and Eccentric Exercise on Chondrocyte Death and Synovial Fluid Proteins in the Rabbit knee
… loading on synovial fluid (SF) composition and chondrocytes viability. The purpose of this study was to load intact knee joints with two types of controlled maximal muscular contractions (low, and high intensity exercise) and identify changes in synovial fluid protein composition and chondrocyte …
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Investigation of the role of Staphylococcus Aureus toxins in a cartilage explant model of septic arthritis
… interaction between S. aureus toxins and in situ chondrocytes during an episode of septic arthritis. An in vitro bovine osteochondral explant model of S. aureus-induced septic arthritis was developed in this study. Utilising fluorescence-mode confocal laser scanning microscopy (CLSM), the model, …
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A Method to Improve Cartilage Integration
… mosaic arthroplasty is the presence of a zone of chondrocyte death (ZCD) that is generated upon osteochondral graft harvest, which can extend up to 400 μm into the cartilaginous portion of the graft. In order for cartilage integration to occur, chondrocytes must be present at the graft periphery; …
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The effects of superoxide dismutase on osteoarticular cells and structural analysis of ochronosis, in a disease model of alkaptonuria
… causes damage to the extracellular matrix and chondrocyte death. It is hypothesised that superoxide dismutase (SOD) may have a beneficial effect on chondrocytes and limit this polymerisation process. This research aims to observe the effects of SOD in an in vitro model of ochronosis, and …
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Osteoarthritis: the role and mechanisms of the chondroprotective peptide Urocortin I
… of OA pathogenesis is currently unknown, chondrocyte death by apoptosis is seen as one of the main contributors to the disease process. It is increasingly recognised that the overproduction of mediators such as Nitric Oxide (NO) in Osteoarthritic cartilage contributes to the disease …