Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"choline metabolism"”.
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Near Infrared Fluorescent Choline Kinase Inhibitors for Cancer Imaging and Therapy
Choline kinase alpha (ChoKa) deregulation is associated with a more aggressive phenotype and greater malignancy in many human cancers. Inhibitors of ChoKa induce apoptosis in tumorigenic cells, but validation of their specificity is difficult in vivo. Alterations in the profile of choline …
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Biochemistry in healthy and neoplastic human tissues: metabolic alteration revealed by HR-MAS nuclear magnetic resonance spectroscopy
… metabolites, that although involved in the metabolism of tumoral tissues in low concentration, can be important modulators of neoplastic proliferation, was performed. In addition, NMR data was integrated with statistical techniques in order to obtain semi-quantitative information about the …
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Poliovirus Replication: Interactions with Cytoplasmic Membranes and with Compounds Which Affect Virus Biosynthesis
… deoxycholate. We have utilized <sup>3</sup>H-choline as a specific precursor of choline-containing phospholipids, to study the synthesis of cytoplasmic membranes. We have confirmed that the incorporation of <sup>3</sup>H-choline into cytoplasmic membranes is greatly stimulated by poliovirus …