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Showing 1 to 20 of 27 for “"cholesteryl ester"”.

  1. Development of a novel cell traction force transducer based on cholesteryl ester liquid crystals. Characterisation, quantification and evaluation of a cholesteryl ester liquid crystal based single cell force transducer system.

    Soon, Chin FhongUniversity of Bradford2012

    … cell traction force transducer system based on cholesteryl ester lyotropic liquid crystals (LCTFT) was developed to sense localised traction forces of human keratinocyte cell lines (HaCaTs), in which the length of the deformation line induced represents the intensity of the CTF exerted. The …

    bradford Repository record

  2. The Effects of Cholesteryl Ester Transfer Protein Inhibition on High Density Lipoprotein Function

    Shrestha, SudichhyaUNSW, Sydney2018

    … elevated plasma high density lipoprotein cholesterol (HDL-C) levels and a reduced risk of major cardiovascular events. HDLs have several potential cardioprotective functions, the most extensively studied of which is their ability to remove excess cholesterol from macrophages. They also have …

    unsw Repository record

  3. THE ROLE OF HEPATIC ACAT2 AND MTP IN HEPATIC CHOLESTERYL ESTER AND TRIGLYCERIDE METABOLISM

    Marshall, Stephanie MarieWake Forest University2013

    … was to delineate the role of the hepatic cholesterol-esterifying enzyme acyl-CoA:cholesterol acyltransferase 2 (ACAT2) in cholesterol balance and triglyceride metabolism.

    wfu Repository record

  4. Investigation of the physical properties of cholesteryl ester liquid crystal and the interaction with cells

    Wan Omar, Wan IbtisamUniversiti Tun Hussein Onn Malaysia2016

    Cholesteryl ester liquid crystals (CELC) were demonstrated with application in biosensing and microtissue regeneration. The affinity of the cells to this liquid crystal is unclear and required further investigation. This study focused on characterising the physical properties of CELC and …

    uthm Repository record

  5. The Influence of Lipid Composition on the Binding of LDL to Chondroitin 6-Sulphate

    Espiritu, Wilma2014

    … temperature, phospholipid content, free cholesterol content, cholesteryl ester content, triglyceride content, and size. Correlations of these characteristics with LDL-C6S binding were analyzed using a turbidity assay. Our results showed that there is no correlation between LDL-C6S binding and …

    vcu Repository record

  6. Uptake and distribution of 3H-cholesteryl oleyl ether in tissues of cholesterol-fed New Zealand White and Watanabe Heritable Hyperlipidemic rabbits

    McCormack, Cynthia J.Boston University1988

    Cholesterol-fed New Zealand White (CH-FED) and Watanabe Heritable Hyperlipidemic (WHHL) rabbits with minimal, moderate, and severe atherosclerosis were injected with a non-degradable cholesteryl ester analogue, 3H-cholesteryl oleyl ether (3H-COE), to identify organs and cells active in the uptake …

    bu Repository record

  7. Altered Cholesterol Metabolism In Human Cancers Unraveled By Label-Free Spectroscopic Imaging

    Yue, Shuhua

    … for human cancers through the study of cholesterol in cancer cells.</p> <p>Enabled by label-free Raman spectromicroscopy, we performed the first quantitative analysis of lipogenesis at single cell level in human patient cancerous tissues. Our imaging data revealed an unexpected, aberrant …

    purdue-thes Repository record

  8. The Dose Response Effect of Almonds on Serum Vitamin E, Plasma Lipid Fractions and Erythrocyte Phospholipids

    Jambazian, Pera

    … were determined in phospholipid, triglyceride, cholesteryl ester and free fatty acid fractions as well as erythrocyte phospholipid fractions. Serum phospholipids were the most responsive fraction, and the addition of almonds to a heart healthy diet significantly decreased the concentration of …

    loma-linda Repository record

  9. The Role of ACAT2 in the Initiation and Treatment of Atherosclerosis

    Melchior, John TrevvettWake Forest University2012

    Hepatic acyl coenzyme A:cholesterol acyltransferase 2 (ACAT2) synthesizes cholesteryl ester (CE) from free cholesterol and fatty acyl-CoA. ACAT2 is responsible for the packaging of cholesteryl oleate (CO) into VLDL secreted from the liver and studies have shown a relationship between both ACAT2 …

    wfu Repository record

  10. THE ROLE OF HEPATOCYTE ATP-BINDING CASSETTE TRANSPORTER A1 (ABCA1) AND APOLIPOPROTEIN M (APOM) IN HIGH DENSITY LIPOPROTEIN (HDL) METABOLISM

    Bashore, Alexander CusaWake Forest University2018

    … protein, functions to transport free cholesterol (FC) and phospholipids across the plasma membrane to apolipoproteins, forming nascent HDL particles. Hepatic ABCA1 is essential in HDL particle formation and maintenance of plasma HDL cholesterol (HDL-C) levels. However, its role in …

    wfu Repository record

  11. ROLE OF HEPATIC APOLIPOPROTEIN M AND ATP-BINDING CASSETTE TRANSPORTER A1 (ABCA1) IN LIPID METABOLISM

    Liu, MingxiaWake Forest University2013

    … mice had larger plasma HDLs enriched with apoM, cholesteryl ester, lecithin:cholesterol acyltransferase and S1P, but not enhanced macrophage reverse cholesterol transport compared to wild type mice. Hepatocytes from transgenic mice generated larger nascent HDLs and stimulated sphingolipid …

    wfu Repository record

  12. Lipid Targets of the Antimalarial Trioxanes in <i>Plasmodium falciparum</i>

    Hartwig, Carmony Leah2019

    … parasites contained increased fatty acids and a cholesteryl ester. <em>in vitro</em> reactions of artemisinin and heme in the presence of digestive vacuole-associated lipids generated fluorescent peroxidation end-products whose formation was inhibited by α-tocopherol.</p> <p>We found that novel, …

    odu Repository record

  13. Assoziationen zwischen Polymorphismen lithogener Kandidatengene und Risikofaktoren der Cholesterincholelithiasis

    Schirin-Sokhan, RaminPublikationsserver der RWTH Aachen University2005

    … to be associated with serum levels of HDL cholesterol, the major source of biliary cholesterol. In addition, established human candidate genes like the apolipoprotein E (APOE) and the cholesteryl ester transfer protein (CETP) were included in the study.Suitable single nucleotide polymorphisms …

    aachen Repository record

  14. The Role of High-Density Lipoproteins and Related Pathways in Alzheimer’s Disease

    Hottman, David2017

    … and metabolism/function. One is through the cholesteryl ester transfer protein (CETP), which transports cholesterol esters and triglycerides between different lipoprotein particles. Loss-of-function mutations in CETP are associated with better cognition in aging. To investigate the role of …

    umn Repository record

  15. Potential functionality and digestibility of oryzanol as determined using in vitro cell culture models

    Huang, Chih-chun JeanSchool of Nutrition and Food Sciences2022

    … be used to study antioxidant activity, hypocholesterolemic capability and digestibility of γ-oryzanol. The critical and vital parameters in developing these cell models were the emulsion preparation of hydrophobic compounds for cell models, the consistent management of cell culture, and the …

    lsu-thes Repository record

  16. Omics Techniques Applied to Diabetes Research - Focus on HSL-Null Mice and Clonal β-Cells

    Fernandez, CelineDepartment of Experimental Medical Science, Lund Univeristy2008

    … show that HSL plays an important role as a cholesteryl ester hydrolase in the liver and that HSL influences overall cholesterol homeostasis by indirectly controlling hepatic HDL-cholesterol clearance. We also demonstrated the importance of a cross-talk between white adipose tissue and liver …

    lund Repository record

  17. Macrophage Activation Profile and Phenotype Are Regulated by Metabolic Pathways and Are Altered by Diabetic Conditions

    Guest, Christopher B.University of Illinois at Urbana-Champaign2015

    … of CD36 and SR-A and the accumulation of cholesteryl ester and acetylated-LDL in primary mouse macrophages to form foam cells similar to those found in atherosclerotic plaques. Finally, macrophages must be capable of integrating numerous metabolic and immune signals. One way they do this …

    uiuc Repository record

  18. Prediction Models and Pharmacogenomics in Adult Growth Hormone Deficiency

    Barbosa, Edna de Jesus Litenski2012

    … after GHRT. At baseline, distinct SNPs of the cholesteryl ester transfer protein (CETP) gene were associated with higher total cholesterol (TC), HDL-C and LDL-C, those of the apolipoprotein E (APOE) gene with lower TC and LDL-C, APOB gene with higher serum HDL-C, and those of the peroxisome …

    goteborg Repository record

  19. Metabolic control of neural stem cell function in a patient-derived model of multiple sclerosis

    Ionescu, Rosana-BristenaUniversity of Cambridge2024

    … elevated synthesis of fatty acids and cholesterol, leading to the accumulation of cholesteryl ester-enriched lipid droplets. Furthermore, the lipogenic state mediated by HMG-CoA reductase activity triggered SASP release in PMS iNSCs via transcriptional regulation by cholesterol-dependent …

    cambridge Repository record

  20. APOE, PCSK9, and CETP genetic variants as potential biomarkers of dyslipidaemia in black South Africans with Type 2 Diabetes Mellitus

    Evans, JonathanDivision of Human Genetics2018

    … convertase subtilisin/kexin type 9 (PCSK9), and cholesteryl ester transfer protein (CETP) are key regulators of plasma cholesterol levels. Thus, genetic variation in the genes coding for these proteins contributes to dyslipidaemia. In this study, a cohort of black South African Type 2 Diabetes …

    cape-town Repository record

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