Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"chlorpromazine (CPZ)"”.
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Repurposing chlorpromazine and its metabolites for antituberculosis drug discovery
… This study aimed to generate metabolites of chlorpromazine (CPZ), a phenothiazine with demonstrated in vitro activity against Mtb, and to investigate their potential utility in combination with anti-TB drugs. 7-HydroxyCPZ (M2), CPZ-N-oxide (M3), CPZ sulfoxide (M1), nor-CPZ (M5), nor-CPZ …
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The regulation of yeast homotypic membrane fusion by class C ABC transporters
… the bilayer fluidity with the addition of chlorpromazine (CPZ) abolished lipid translocation activity and propranolol inhibition of phosphatidic acid phosphatase activity increased the rate of lipid translocation.
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Lipid composition and membrane physical parameters regulate priming and SNARE function in yeast vacuole membrane fusion
Fusion at highly specialized membrane microdomains is a prerequisite for processes like hormone and neurotransmitter release, antigen presentation and viral infection. Apart from a family of highly conserved proteins called SNAREs, membrane fusion also requires a set of regulatory lipids that …