Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 11 of 11 for “"chiral catalysts"”.
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CoMFA Study of Chiral Catalysts
… Analysis (CoMFA) is developed for a set of 23 catalysts containing bis-oxazoline or phosphino-oxazoline ligands that are known to induce asymmetry during the Diels-Alder reaction of N-2-alkenoyl-1, 3-oxazolidine-2-one with cyclopentadiene. It is shown that extemely high q2 statistics can be …
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Application of asymmetric C-‐H activation to the synthesis of Planar Chiral Catalysts and Ligands.
… al. for the generation of enantioenriched planar chiral palladacycles.1. The first of which includes the synthesis and application of symmetrical and non-‐symmetrical phosphines, and in this work the latter have been transformed into a diastereomerically pure enantiomerically enriched …
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Improved synthesis and application of planar-chiral nucleophilic catalysts in asymmetric reactions and copper-catalyzed enantioselective N-H insertion reactions
… of an improved synthesis of nucleophilic planar-chiral catalysts is described in Chapter 1. This route is amenable to scale-up and preparative chiral HPLC is unnecessary to resolve the racemic catalysts. Using planar-chiral catalysts, two synthetic methodology projects have been developed: …
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Explorations with optically active, cage-annulated crown ethers.
… have been prepared via incorporation of chiral elements into the crown ring skeleton. The ability of these crown ethers to recognize the enantiomers of guest salts, i.e., (+) a-methyl benzylamine and to transport them enantioselectively in W-tube transport experiments were studied. The …
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Asymmetric cyclopropanation via catalysts incorporating the 1,4-diol ligands and the newly designed dioxaborolane /
… new methodology for the asymmetric synthesis of chiral organic compounds is a major focus in modem organic chemistry. The use of chiral catalysts is replacing chiral auxiliaries as a new tool for synthetic chemists. An efficient chiral catalyst allows for large quantities of optically active …
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Nickel-catalyzed asymmetric cross-couplings of secondary allylic chlorides and planar-chiral compounds in asymmetric synthesis
… fluvirucinine A1. In Part II, the use of planar-chiral compounds as ligands or catalysts in organic synthesis is described. A C2-symmetric planar-chiral bipyridine is an efficient ligand for copper-catalyzed asymmetric [4+1]-cycloadditions between enones and diazoacetates to form …
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The Application and Evolution of Chiral Ion-Paired Rhodium(II,II) Tetracarboxylate Catalysts for Enantioselective Nitrene Transfer
… nitrene transfer chemistry employing chiral ion-paired dirhodium catalysts. The initial development of this catalyst family was reported previously by the Phipps group and their design is based on a strategy for the combination of transition metal complexes and cinchona …
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DEVELOPMENT OF BASE METAL-CATALYZED HYDROGEN TRANSFER AND CROSS-COUPLING REACTIONS
… of this thesis is focused on (i) the use of iron catalysts for reactions involving hydrogen transfer and (ii) the development of nickel-catalysed C-heteroatom coupling reactions following the ‘metallaphotoredox’ approach exploiting readily available organic photocatalysts. Thanks to their …
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Oxo-metal catalysed reactions of unsaturated alcohols
… (particularly molybdenum and vanadium) as catalysts for a number of synthetically important reactions is described. The ability of alkyl hydroperoxides to epoxidise alkenes in the presence of transition metal catalysts is well known and is reviewed here along with the more conventional …
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The modification of brucine derivatives as chiral ligands and its application in the asymmetric synthesis
<p>The modification of brucine derivatives as chiral ligands and the use of a multifaceted chiral ligand, brucine diol, under different reaction conditions to produce various optical isomers is described. In Chapter 1, the generation of a number of brucine derivatives is described. Taking the …
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Functional dna: Biochemical/biophysical characterization & sensing applications
… and functionally valuable molecules are chiral, such as pharmaceuticals and chiral catalysts. For example, Xopenex,® a single enantiomer form of albuterol, has higher efficacy than the racemic mixture. There are currently multiple methods for determining the enantiomeric ratio, all of …