Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 16 of 16 for “"chemical stimulation"”.
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Electro-chemical stimulation of neuromuscular systems using ion-selective membranes : flexible device fabrication and motor unit recruitment order
… costs. Direct nerve Functional Electrical Stimulation (FES) induces muscles to contract by electrically stimulating nerves, which shows promise for clinical applications in restoring muscle function in SC. However, Functional Electrical Stimulation is limited by the lack of graded response …
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On chemical stimulation in rat erythrocytes of glucose oxidation via the pentose pathway, and the inhibition of this stimulation by sodium chromate and 2,5-dinitrobenzoic acid
This document only includes an excerpt of the corresponding thesis or dissertation. To request a digital scan of the full text, please contact the Ruth Lilly Medical Library's Interlibrary Loan Department (rlmlill@iu.edu).
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Chemotaxis Methyltransferase Ii From Bacillus Subtilis
… by which motile cells sense and respond to their chemical environment. Following a period of time during which chemotactic bacteria respond to chemical stimulation, they revert to their pre-stimulus behavior, or adapt. Biochemically, adaptation is correlated with the methylation or demethylation …
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Characterisation of dynamics associated with skeletal muscle contraction initiated by Acetylcholine injection Ghabiba Modak.
… directly by means of Functional Electrical Stimulation (FES), which requires 100-1000 times more current than that required for nerve stimulation, thus presenting the risk of pain receptor activation. A potential alternative exists in chemical stimulation by means of administration of the …
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Development of light actuated chemical delivery platform on a 2-D array of micropore structure
<p>Localized chemical delivery plays an essential role in the fundamental information transfers within biological systems. Thus, the ability to mimic the natural chemical signal modulation would provide significant contributions to understand the functional signaling pathway of biological cells and …
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Microfluidic Concentration Gradient Generation and Integrated Magnetic Sorting of Microparticles
… which are often performed in series, i.e., chemical stimulation of cells (cell treatment and chemotaxis) and cell sorting. For chemical stimulation of cells, rapid and novel designs of concentration gradient generation (CGG) devices are presented; for cell sorting, a magnetically The most …
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Chemesthesis in the Earthworm, Lumbricus terrestris: The search for TRP Channels
Chemesthesis is the chemical stimulation of receptors on somatosensory neurons usually by noxious chemicals leading to irritation. Transient receptor potential channels play a major role in detecting chemesthetic stimuli and are found in a wide variety of organisms, from yeast to humans. Currently, …
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Genetically encodable calcium sensors for Magnetic Resonance Imaging
… nitric oxide synthase (nNOS). We show that chemical stimulation of ectopically expressed neuronal nitric oxide synthase (nNOS) elicits an artificial hemodynamic response detectable by MRI. To distinguish signaling from endogenous nNOS we use a two-prong strategy to engineer a suite of …
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Supramolecular architectures for neural prostheses
… with the neural tissue should be performed via chemical rather than electrical messages. However, catastrophic destruction of neural tissue due to the release of large quantities of a neuroactive species, like neurotransmitters, precludes the storage of quantities large enough to suffice for the …
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An Account of Chemical and Mechanical Regulation of TRPC6 Channels in Podocytes
… are polymodal and can be activated by either chemical or mechanical stimuli. Chemical stimulation is mediated by surface-expressed receptors, and the roles of angiotensin II type 1 receptors (AT1R), insulin receptors, and N-methyl-D-aspartate receptors (NMDAR) on TRPC6 activity are studied …
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Nucleus accumbens dopamine and investigatory behavior : modulation by the ventral subiculum of the hippocampus through the dopamine cell bodies of the ventral tegmental area
… fluctuations in DA release in response to chemical stimulation of the VS by injections of the excitatory amino acid analog N-methyl-D-aspartate (NMDA). Such injections increased investigatory behavior and elevated dopamine in both the DA terminal region of the NAS and the DA cell body …
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Characterization of peptide release from neuronal cells with microfluidics and mass spectrometry
… between these cells often relies on chemical signals. Deciphering these signaling molecules, including neuropeptides, is an important but challenging task. Microfluidic technology allows the manipulation of mass-limited samples and the control of the extracellular microenvironment, …
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Neural processing of chemosensory information from the locust legs
… insects can provide information on the chemical nature of the leaf surface, and are thus potentially important in host plant discrimination. Ovipositing Pieris brassicae, for example, drum the surface of leaves with their tarsi and tarsal chemoreceptors have been shown to respond to …
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The mechanical regulation of Semaphorin3A signalling in the developing Xenopus laevis brain
… the developing brain interpret gradients of both chemical and mechanical cues for navigation. In this thesis, I investigated how these two signalling modalities interact to achieve robust axon guidance, using the Xenopus retinotectal system as a model. Specifically, I studied how the response of …
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COORDINATED PHENOMENA IN THE MARINE DEMOSPONGE CHONDROSIA RENIFORMIS: PHYSIOLOGICAL, MORPHOLOGICAL, BIOMECHANICAL AND BIOCHEMICAL ASPECTS.
… it can rapidly stiffen after mechanical or chemical stimulation or destiffen and, following accidental detachment of the substrate, produce long slender outgrowths. These phenomena involve different responses induced by different external events, but both have been attributed to alteration, …
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Membrane properties and calcium ion activity in skeletal muscle fibres of the dystrophic mouse
… not generate tension from either electrical or chemical stimulation. Older muscles generated tension but smaller than their normal counterparts. Twitch and contracture tomography revealed similarities between dystrophic EDL and immature normal EDL corroborating with the conclusions made from the …