Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 33 for “"chemical exposure"”.
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Association Between Smoking, Chemical Exposure and Hearing Loss in an Occupational Setting
… the association between smoking, workplace chemical exposure, and hearing loss.Methods: This cross-sectional population-based study was conducted in an occupational health clinic setting in Virginia. The study population consisted of employees from local businesses who visited the clinic …
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Estimating the dermally absorbed dose from chemical exposure: data analysis, parameter estimation, and sensitivity to parameter uncertainties
Includes bibliographical references (page 464).
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DNA FRAGILE SITE BREAKAGE AS A MEASURE OF CHEMICAL EXPOSURE AND PREDICTOR OF THE SUSCEPTIBILITY TO FORM CHROMOSOMAL REARRANGEMENTS
… These DNA breaks can occur through exogeneous chemical exposures and/or at regions particularly susceptible to breakage termed “common fragile sites (CFS)”. To test the hypothesis that fragile site breakage underlies the formation of chromosomal rearrangements, we focused on RET/PTC …
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Environmental Stressors: Pathways Of Exposure And Aquatic Invertebrate Response
… various matrices (i.e., sediment and water) to chemical exposure is critical for remediation of impacted sites. </p> <p>To evaluate various matrices of chemical exposure, I focused on the organic pollutant polychlorinated biphenyls (PCBs) due to their relatively ubiquitous nature, high toxicity, …
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The urinary excretion of amino acid conjugates in free living adult males
… tobacco, alcohol, caffeine, and marijuana use; exposure to chemicals and familial cancer incidence) on the urinary excretion of the amino acid conjugates were investigated. Three consecutive 24 hour urines were collected from 40 subjects who complied with a specific collection protocol. The …
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Bayesian and Frequentist Approaches for the Analysis of Multiple Endpoints Data Resulting from Exposure to Multiple Health Stressors.
… is used to quantify the risk associated with exposure to stressors such as environmental chemicals. It consists of fitting a mathematical model to the exposure data and the BMD is the dose expected to result in a pre-specified response or benchmark response (BMR). Most available exposure data …
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Assessing Brook Stickleback (Culaea inconstans) as a bioindicator for endocrine disrupting compounds in aquatic environments
… which can be used to assess (anti-)androgenic exposure. EDC assessment in the field using threespine stickleback and the spiggin biomarker is limited to coastal and estuarine environments. However, their freshwater relative, brook stickleback (Culaea inconstans), also possess spiggin and their …
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PTSD and Immunological Correlations Of Attention and Working Memory in Gulf War Illness
… difficult to ascertain the influence of trauma exposure and chemical exposure when investigating neuropsychological symptoms. This cross-sectional study utilized a group of veterans with and without GWI (n=61) to investigate: 1) the unique impact that GWI has on a survey measure of attention and …
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Sorption and biodegradation of phenanthrene in soils
… information on the behavior of organic chemicals in the subsurface environment is needed for effective remediation. The purpose of this study was to investigate the relationship between sorption and biodegradation on the ultimate fate of subsurface contaminants. Sorption and …
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Investigating Droplet Impact Dynamics on Engineered Surfaces: Effects of Roughness, Wettability, and Prospects for Anti-Icing Applications
… under stress, such as scratching, peeling, and chemical exposure. These tests identified critical points where surfaces start to lose their water-repellent and anti-icing properties, providing valuable insights into how to enhance material durability. The work also developed a custom-built …
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Advancing Chemical Hazard and Risk Assessments: Insights From Chemical Property Prediction and Multimedia Mass-Balance Modeling
… and risks associated with the vast array of chemical substances on the market is essential for protecting human health and environmental integrity. Chemical properties serve as critical determinants of a chemical's potential for hazard, exposure, and risk. By evaluating both the inherent …
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Atrazine: a lively chemical journey
… and reproductive toxicity led the EU to ban the chemical in 2003. Despite long standing evidence of its harm, South Africa continues to use atrazine, the majority of which is imported from the EU. Drawing on South Africa as a case study, I illustrate Atrazine's unique journey through South …
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The use of different blood sample preparations in the development of biomarkers for the environmental monitoring of domestic farm animals
… monitoring for the detection of environmental chemical exposure in domestic animals is still in its infancy. This study investigated blood sample preparations in vitro for their use in biological effect monitoring. When peripheral blood mononuclear cells (PBMCs), isolated following the …
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Approaches to understanding the cumulative effects of stressors on marine mammals.
… and the nonlymphoma adult. POP life history exposure profiles were reconstructed using baleen whale earplugs. This earplug study expands upon previous earplug studies of both spatial and temporal trends. POPs analysis using earplugs provided contaminant data 30 years prior to the first …
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Medical Underservice and Cancer Mortality Among Farmers in Illinois
… cancer types thought to be associated with farm chemical exposure. Rural nonfarm populations evidenced decreased risk of mortality for most cancer types. In comparing the nonfarm study groups, the only statistically significant difference was an increased risk for prostate cancer in the …
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Alteration of differentiation and growth of normal human epidermal keratinocytes by benzo[a]pyrene and arsenic
… G2 phase. Differentiation is more sensitive to chemically-mediated perturbations than is proliferation, indicating that the former process may be the initial target at environmentally prevalent concentrations. To identify molecular alterations that are responsible for the observed …
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Characterisation of feed and membrane properties for industrial ultrafiltration management
… impact of membrane modification and increasing chemical age on fouling behaviour. To assess commonly applied foulant characterisation methods, fluorescence excitation emission (FEEM) spectroscopy and liquid chromatography organic carbon detector (LC-OCD) were used to characterise proteins of …
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Multi-Cellular Organotypic Liver Models for the Investigation of Chemical Toxicity and Liver Fibrosis
… liver fibrosis. There are tens of thousands of chemicals with undetermined effects on the human body. High concentrations of xenobiotics can cause acute liver damage and failure. Liver impairment can result in multiple organ failure, hepatic encephalopathy and death. Therefore, it becomes …
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An informatics approach to prioritizing risk assessment for chemicals and chemical combinations based on near-field exposure from consumer products
Over 80,000 chemicals are registered under the U.S. Toxic Substances Control Act of 1976, but only a few hundred have been screened for human toxicity. Not even those used in everyday consumer products, and known to have widespread exposure in the general population, have been screened. Toxicity …
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Alkyl Polyglucoside Compound Influences Freshwater Plankton Community Structure in Floating Mesocosms
… Although APGs degrade rapidly and reduce chemical exposure time, they can still have toxic effects on aquatic organisms, and microbial oxygen consumption increases during the process of biodegradation. Despite being 2-12 times less toxic than synthetic surfactants such as alcohol …
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