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Showing 1 to 6 of 6 for “"checkpoint recovery"”.
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Mathematical Modeling Reveals That G2/M Checkpoint Override
<p>Cell cycle checkpoints determine whether cells meet requirements to progress through the next stage. In response to DNA damage, how cells activate checkpoints have been well studied, but little is known about checkpoint deactivation (recovery), which directly impacts on cell fate. In tumor …
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Mathematical Modeling Reveals That G2/M Checkpoint Override Creates A Therapeutic Vulnerability In Tsc2-Null Tumors
<p>Cell cycle checkpoints determine whether cells meet requirements to progress through the next stage. In response to DNA damage, how cells activate checkpoints have been well studied, but little is known about checkpoint deactivation (recovery), which directly impacts on cell fate. In tumor …
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Mathematical Modeling Reveals That G2/M Checkpoint Override Creates A Therapeutic Vulnerability In Tsc2-Null Tumors
<p>Cell cycle checkpoints determine whether cells meet requirements to progress through the next stage. In response to DNA damage, how cells activate checkpoints have been well studied, but little is known about checkpoint deactivation (recovery), which directly impacts on cell fate. In tumor …
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Scalable Diskless Checkpointing for Large Parallel Systems
… to investigate the performability of diskless checkpointing. Our model evaluation shows that the overhead of checkpoint/recovery is small on systems with thousands of nodes, and with appropriate partitioning of nodes, the user application can survive several times longer.
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Characterization of Histone H2A Functional Domains Important for Regulation of the DNA Damage Response
… that the SRS motif is required for efficient checkpoint recovery following successful repair, a function independent of post-translational modifications. Another contribution of histone H2A in S. cerevisiae, specific to the MMS induced DNA damage response, is provided by the three …
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Practical Mitigations Against Memory Corruption and Transient Execution Attacks
… to protect energy harvesting devices from checkpoint-recovery errors and malicious attackers.