Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 1 of 1 for “"chaperon-mediated autophagy"”.
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Jab1 Negatively Regulates Pten and Promotes Resistance to Trastuzumab In Her2-Positive Breast Cancer
… breast cancer. I demonstrated that Jab1 mediated the post-translational regulation of PTEN by associating with PTEN and facilitating its degradation. I also found that the C-terminal end of Jab1 was required for Jab1 to induce degradation of PTEN. Furthermore, I showed that proteasome …