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Showing 1 to 1 of 1 for “"channel activating protease"”.

  1. Channel activating proteases: molecular targets for correction of sodium channel dysfunction in cystic fibrosis airways disease

    … evaluate three novel inhibitors of trypsin-like channel activating proteases to determine their effect on inflammatory signaling via PAR-2 and also on ENaC activity in CF airway epithelial cells (AECs). Further, two highly selective and potent furin inhibitors, BOS-981 and BOS-318 were …

    qu-belfast Repository record for Channel activating proteases: molecular targets for correction of sodium channel dysfunction in cystic fibrosis airways disease (opens in a new tab)