Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 21 for “"chain formation"”.
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STRUCTURAL INSIGHTS INTO POLYUBIQUITIN CHAIN FORMATION MEDIATED BY NEDD4 HECT LIGASE
… prompt the release of its closed conformation enabling substrate ubiquitination. From the catalytic point-of-view, NEDD4 can modify substrates with a single ubiquitin moiety or K63-linked polyubiquitin chains. Despite its critical role, the structural and mechanistic aspects of …
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Computational Studies of Electrorheological Emulsions
… numerical results in different regions of the deformation-circulation map show that the structure formation in regions I and III can be hindered by the hydrodynamic effect. This is opposite to what is observed in the perfect dielectric cases and region II of the map. For perfect dielectric …
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Um método estocástico de alocação de memória
… theory to the mathematical interpretation of the chains of pages that link two given pages of the program in the computer. Then noticing randomnes as a main factor in the developed structure, we introduce some result that explain the law of formation of these chains. There after, we introduce the …
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The Syntax and Typology of Bantu Relative Clauses
… employ to avoid violating general conditions on chain formation. The specific system argued for includes a derivational system of syntax in which only unvalued features are probes, probes are unrestricted with regard to the direction of probing, and the locality of syntactic relations is a …
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Nicotinamide Riboside Delivery Generates NAD+ Reserves to Protect Vascular Cells Against Oxidative Damage
… by a striking increase in nuclear PAR-chain accumulation. PARP inhibition abolished PAR-chain formation and preserved NAD+ levels, establishing PARP in NAD+ consumption in this model. NR delivery protected against cell-shrinkage and cell death and promoted DNA repair efficiency. PARP …
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Essays in network economics
… paper. The first chapter studies how the formation of supply chains affects economic growth. It provides a new tractable model for supply chain formation. The main innovation in this model is that, firms can choose suppliers to maximize profits. Individual firms' actions determine the …
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Semantic Text Analytics Technique for Classification of Manufacturing Suppliers
Most of the information available in the manufacturing industry is in unstructured, natural language format. The unstructured data could contain important and useful information that can inform decision makers across different phases of product lifecycle. However, due to its unstructured nature, it …
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바이러스 감염시 미토콘드리아 E3 ubiquitin ligase 인 MARCH5의 새로운 생체 기능
… revealed that MARCH5 facilitated polyubiquitin chain formation at HBx protein and its proteasome-dependent degradation. Taken together, MARCH5 is a crucial mitochondria-resident regulator that plays a protective role against accumulation of aggregated MAVS and HBx.
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Non-equilibrium self-assembly processes of complex dipolar colloids
… interactions on the non-equilibrium structure formation in quasi-two dimensional colloidal systems. On the one hand, theoretical models for certain experimentally realized systems are developed and investigated by means of Brownian Dynamics Simulations. To estimate phase transitions, basic …
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In-Depth Study of Different Magnetorheological Fluid Properties Under Different Operating Parameters, and in Presence of Organic Additives
… for various damping systems. As MRFs form chains, MRFs transit from a liquid state to a solid-like state exhibiting an increase in viscosity. Since MRF discovery, commercialization, and enhancement of MRF performance in earthquake dampers, is the focus of interest to protect 10k lives lost …
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Manipulative Scanning Tunneling Microscopy and Molecular Spintronics
… resonances, surface catalyzed covalently bound chain formation, and spintronic interactions of organically coupled magnetic ions. Local work functions are found, by analyses of field emission resonances, for probe induced surface vacancies and atomic step edges on an atomically clean Ag(111) …
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Investigating the response of the NEDD8 ubiquitin-like molecule to diverse stress conditions
… mass spectrometric analyses to investigate NEDD8 chain formation under stress. We found that NEDD8 forms chains with itself and with ubiquitin, and these chains are recognized by proteasome receptors and shuttle factors. Our studies revealed an unprecedented interplay between NEDD8 and ubiquitin …
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Structural Insights into TRIM21 Ubiquitination Mechanisms
… enzymes and how it utilizes these for ubiquitin chain formation. Previous work suggested that TRIM21 requires the E2 enzymes Ube2W and Ube2N/Ube2V2 to build K63-linked ubiquitin chains and drive anti-viral function. My work reveals how TRIM21 facilitates ubiquitin transfer and differentiates …
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Hrd1 Partners In Endoplasmic Reticulum-Associated Degradation
… suggesting that specific types of ubiquitin chains are formed in ERAD under varying conditions. These findings led us to wonder whether HRD1 makes different types of ubiquitin-ubiquitin linkages with different E2 ubiquitin-conjugases. Through in vitro reconstituted systems, we found that HRD1 …
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Molecular Self-assembly of Functionalized Pentacenes and Fullerenes on Metal Surfaces by STM and DFT Investigations
… deposited C60 molecules form long parallel chains with a rectangular arrangement atop the intact DCP SAM on Au(788). The C60 molecular chain is commensurate (3:2) with the DCP lattice along the long axis: three fullerenes line up with two DCP molecules. The C60 adlayer serves as the …
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Determination of the Composition and Architecture of the Mitochondrial Ubiquitome in PINK1/Parkin Mitophagy
… has been done to establish the substrates and chain type composition of the Ub placed on mitochondrial substrates by Parkin, little work has been done to establish the broader Ub chain architecture: the degree of chain branching, and the relationship between phosphorylation and chain formation …
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Investigation Of Parameters Enabling Admicellar Reversible Addition-Fragmentation Chain Transfer (Raft) Polymerization
… early termination and increases the rate of dead chain formation. Admicellar polymerizations using the water-soluble initiator exhibited higher Mw polymer compared to the systems using the water-insoluble initiator due to less degree of partitioning of water-soluble initiator in the admicelle …
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Measurement of displacements in granular systems in response to penetration and compaction
… porosity, initial particle arrangement and force chain formation, were investigated. Samples which were conducive to the formation of force chains spanning the whole sample were discovered to have anomalously high strengths. Small amounts of added water were shown to increase the compactability, …
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MUTACIN IV PRODUCTION IN STREPTOCOCCUS MUTANS UA159: CHARACTERIZATION, REGULATION, AND MECHANISM OF SELF-IMMUNITY
… a protein, SMU.832, required for glucose side chain formation, can also regulate mutacin production in this organism. Collectively, our data encourage us to propose a new model for regulation of mutacins production in S. mutans UA159. According to our model, peptide pheromone (BipC) is secreted …
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Collective behavior of colloidal suspensions under electric fields and confinement
… alone are shown to be characterized by particle chaining along the field direction, chaining is not found to occur when induced-charge electrophoresis occurs as well, which instead causes transient particle pairings and results in a non-uniform microstructure with large number density …
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