Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"cerebral cortex development"”.
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Spatial and temporal regulation of cerebral cortex development by the transcription factor pax6
Lamina formation in the developing cortex requires precise generation, migration and differentiation of cortical neurons. Cortical projection neurons originate from progenitors of the embryonic dorsal telencephalon. The transcription factor Pax6 is expressed in apical progenitors (APs) throughout …
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Single cell transcriptomic analysis of autism associated gene expression in human cerebral cortex development
Autism spectrum disorder (ASD) is a range of developmental brain disorders characterized by poor nonverbal communication skills, impaired behaviour and social interaction, and a limited diversity of social activities and interests. As the most common pervasive developmental disorder, it affects …
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The Role of CNTNAP2 in the Development & Evolution of the Human Cerebral Cortex
… by species-specific features of their development. Excitatory neurons in the human cerebral cortex have longer neurites and more elaborate neurite branching than chimpanzees or macaques, which is thought to contribute to differences in neural network performance. To study how …
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Role of Laminin gamma 1 in Cortical Development
… in the nervous system. These mice show cortical developmental abnormalities including undulations in the embryonic cortical plate and resultant adult cortical layers and abnormal positioning of pyramidal neurons and interneurons. We have investigated the mechanisms underlying these abnormalities. …